Causes of Acute Appendicitis

Written by Ren Zheng Xin
Gastroenterology
Updated on September 08, 2024
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The causes of acute appendicitis mainly include two types: one is the obstruction of the appendiceal lumen, and the other is infection within the appendiceal lumen. The appendix is a tube that communicates with the cecum. If it is blocked by fecoliths or fecal masses, it can lead to increased pressure inside the appendiceal lumen, damage to the mucosa, and bacterial invasion causing infection, which directly leads to acute inflammation. At the same time, gastrointestinal dysfunction can also cause spasm of appendix muscles and blood vessels, leading to blood supply disturbances. Irregular lifestyle habits, overeating, and engaging in vigorous activities after meals can all trigger acute appendicitis.

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Written by Ren Zheng Xin
Gastroenterology
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How is acute appendicitis treated?

Acute appendicitis treatment primarily involves surgical methods, where the inflamed, suppurative, or perforated appendix is excised during the procedure, and then the base of the appendix is sutured. Moreover, if there is suppuration, it is necessary to irrigate the peritoneal cavity to prevent intra-abdominal infections. After the surgery, fluid therapy should be administered based on the patient's condition. In cases of perforation or suppuration, antibiotics should be used post-operatively. For simple appendicitis, post-operative fluid replenishment is generally sufficient, and antibiotics are not required. (Please use medications under the guidance of a doctor.)

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Written by Ren Zheng Xin
Gastroenterology
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The cause of acute appendicitis

The etiology of acute appendicitis is directly related to obstruction and infection of the appendiceal lumen. The appendix, a narrow and elongated tube connected to the cecum, can develop increased luminal pressure due to obstruction, leading to disturbances in the blood supply to the appendiceal wall. This can easily cause damage to the mucosa and subsequent infection. Infection of the appendiceal lumen can directly cause acute appendicitis. Additionally, gastrointestinal dysfunction can also cause muscle and vascular spasms in the appendix leading to blood supply disturbances and the invasion of bacteria, resulting in acute inflammation. For acute appendicitis, surgical treatment should be administered immediately upon diagnosis.

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Written by Ren Zheng Xin
Gastroenterology
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Which is more serious, acute appendicitis or chronic appendicitis?

Acute appendicitis is relatively common in clinical practice with severe symptoms. Compared to chronic appendicitis, acute appendicitis can cause the appendix tube to become purulent and perforate, leading to a widespread peritonitis. Severe peritonitis can cause multi-organ failure and even shock. Chronic appendicitis, on the other hand, mainly manifests as chronic abdominal pain and seldom shows signs of appendix perforation. It primarily leads to an abscess around the appendix, encapsulating the appendix and causing repetitive chronic pain, which is difficult to heal. Both acute and chronic appendicitis should be treated surgically by removing the appendix to achieve a complete cure.

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Written by Ren Zheng Xin
Gastroenterology
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Typical symptoms of acute appendicitis

The typical symptoms of acute appendicitis include abdominal pain, which starts in the upper abdomen or around the navel and, after several hours, shifts and localizes to the lower right abdomen. Additionally, reflexive gastric spasms may cause nausea and vomiting. Due to the inflammation, the body may develop a fever, generally not exceeding 38 degrees Celsius. If the inflammation affects the parietal peritoneum, it can cause tenderness, rebound pain, and abdominal muscle rigidity. These are the typical symptoms, and a preliminary diagnosis can usually be made based on them. Most cases require an appendectomy.

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Written by Ren Zheng Xin
Gastroenterology
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Early symptoms of acute appendicitis

The symptoms of the early stage of acute appendicitis primarily include vague abdominal pain, initially across the abdomen, then transitioning around the belly button, and after several hours, shifting to the lower right abdomen where the pain becomes localized. The early symptoms of acute appendicitis are not typically distinctive, with the onset being quite sudden, accompanied by severe abdominal pain, vomiting, and fever. Based on these typical clinical manifestations, diagnosing acute appendicitis is not difficult. Clinically, the main treatment is the surgical removal of the appendix, with laparoscopic appendectomy being the more common practice nowadays. This method involves less bleeding during the operation and a quicker post-operative recovery.