For patients with vulvitis, the main complications are the formation of vulvar ulcers or eczema. In chronic inflammation, the skin of the vulva may become thickened, rough, or cracked, and even undergo lichen-like changes. In severe cases, the condition may cause fever and other systemic symptoms, and even lead to enlargement of the inguinal lymph nodes. Furthermore, vulvitis and its pathogens might spread upwards, causing an onset of pelvic inflammatory disease.