Premature rupture of membranes is a common condition during pregnancy, which can easily lead to premature birth and intrauterine infection of the fetus. Prevention should be the primary focus for premature rupture of membranes. Firstly, the most common cause of premature rupture of membranes is infection. For instance, conditions like vaginitis or cervicitis can lead to chorioamnionitis, which in turn can cause the membranes to rupture spontaneously, resulting in the leakage of amniotic fluid. Secondly, excessive pressure within the amniotic cavity can also cause membrane rupture, such as in the case of excessive amniotic fluid. Therefore, during pregnancy, it is important to manage inflammation and control the amount of amniotic fluid. This can help lower the risk of premature rupture of membranes and prevent premature birth and intrauterine infection.