Premature rupture of membranes causes and symptoms

Written by Zhang Lu
Obstetrics
Updated on December 16, 2024
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The symptoms of premature rupture of membranes include the following aspects: First, the most important symptom is the intermittent discharge of clear fluid from the vagina, which is often the most typical symptom of premature rupture of membranes. Second, abdominal pain can occur, as the rupture of the membranes can stimulate contractions causing pain. Third, sometimes there may be a small amount of spotting, mainly due to a small amount of bleeding caused when the membranes rupture. The causes of premature rupture of membranes include the following aspects: First, excessive amniotic fluid can cause high pressure inside the amniotic cavity, which may sometimes lead to spontaneous rupture of the membranes. Second, if there is local inflammation, such as chorioamnionitis, it can also cause the membranes to rupture under severe conditions, leading to premature rupture of membranes.

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Written by Yue Hua
Obstetrics and Gynecology
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Premature rupture of membranes requires what examinations?

To diagnose premature rupture of membranes, first, a pH test of the vaginal fluid must be conducted. The normal pH value of vaginal fluid in women ranges from 4.5 to 5.5, whereas the pH of amniotic fluid ranges from 7.0 to 7.5. If the membranes have ruptured prematurely, the pH value would be greater than 6.5. Additionally, a smear test of the vaginal fluid can be done by placing vaginal secretions under a glass slide and examining them under a microscope. If fern-like crystals are observed, this indicates the presence of amniotic fluid. Furthermore, an ultrasound examination can be conducted. If the ultrasound shows a rapid decrease in the amount of amniotic fluid, this can assist in the diagnosis.

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Written by Du Rui Xia
Obstetrics
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Is premature rupture of membranes dangerous?

When preterm premature rupture of membranes occurs, it can have certain impacts on both the pregnant woman and the fetus. The risks of preterm premature rupture of membranes primarily include the possibility of umbilical cord prolapse, preterm birth, or infection during pregnancy. If the presenting part of the fetus has not descended and the umbilical cord slips into the vagina, umbilical cord prolapse can easily occur, which is very dangerous and can lead to fetal hypoxia or even stillbirth. After the rupture of membranes, bacteria originally present in the vagina may take this opportunity to enter the uterus, causing chorioamnionitis or endometritis. If the infection is not controlled in time, sepsis may also occur.

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Written by Zhang Lu
Obstetrics
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Premature rupture of membranes' impact on the fetus

Premature rupture of membranes (PROM) refers to the rupture of the amniotic sac before the onset of labor, primarily affecting the fetus in the following ways. First, PROM can easily lead to premature birth, which may cause immature development of the fetus, often requiring treatment in neonatology. Second, PROM can lead to infections within the uterine cavity, subsequently causing newborn infections that can lead to neonatal death. Third, during the treatment of PROM, complications such as placental abruption or umbilical cord prolapse may occur, which can easily cause intrauterine hypoxia or death of the fetus. For PROM, it is essential to undergo proper treatment and monitoring. If any abnormalities arise, it is crucial to terminate the pregnancy promptly.

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Written by Zhang Lu
Obstetrics
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The harms of premature rupture of membranes infection

After premature rupture of membranes, because the amniotic cavity is open, some pathogens can cause intrauterine infections through ascending infections. If an infection occurs after premature rupture of the membranes, the harm caused mainly affects the mother and fetus, divided into the following two aspects: First, the impact on the fetus is that it is easy for the fetus itself to become infected, which can lead to congenital neonatal infections after birth, and in severe cases, it may cause fetal death. Second, it can cause maternal infection. If the infection is only limited to the amniotic cavity, sometimes the impact on the mother is not significant. However, if the infection spreads locally, such as into the pelvic cavity, or spreads through the bloodstream, it can cause a systemic inflammatory response, sometimes causing high fever, and in severe cases, it can lead to septic shock.

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Written by Zhang Lu
Obstetrics
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Premature rupture of membranes how is it shown on ultrasound?

Ultrasound is a commonly used auxiliary method for diagnosing premature rupture of membranes. After the membranes rupture prematurely, amniotic fluid intermittently leaks out from the uterine cavity, but the production of amniotic fluid often cannot keep up with the leakage. Therefore, the majority of pregnant women with premature rupture of membranes will experience a reduction in amniotic fluid volume. Ultrasound will reveal that there is still a small amount of amniotic fluid in the amniotic cavity, but the volume is much lower than the normal range; the maximum depth of the amniotic fluid should be less than three centimeters, and the amniotic fluid index should be less than eight centimeters, which is a common occurrence. However, sometimes, if not much amniotic fluid leaks out after premature rupture of membranes, the ultrasound may sometimes show that the amniotic fluid volume is normal. In such cases, it is necessary to combine this finding with the patient's clinical symptoms to jointly determine the presence of premature rupture of membranes.