Premature rupture of membranes is a common condition during pregnancy, and the following aspects should be noted for premature rupture of membranes: First, it is essential to confirm the diagnosis of premature rupture of membranes. Women who experience abnormal vaginal discharge should seek medical examination at a hospital to determine if there is premature rupture of membranes, as missed diagnoses that delay treatment are common in clinical practice. Second, it is crucial to follow standardized treatment for premature rupture of membranes. Depending on the gestational age, decisions on whether to attempt to preserve the pregnancy should be made. Generally, if the condition is stable before thirty-four weeks without fetal hypoxia or infection, it may be appropriate to prolong the pregnancy. After thirty-four weeks, since the viability of the fetus is generally higher, excessive prolongation of the pregnancy is not usually recommended. Third, it is important to prevent infection in cases of premature rupture of membranes. Once the membranes rupture, the amniotic cavity is exposed, making it easy for vaginal bacteria to enter and cause an intrauterine infection. Fourth, attention should be paid to rest in a recumbent position after premature rupture of membranes, as standing or being active might lead to prolapse of the umbilical cord.