Melanoma is a very terrifying disease. Once melanoma develops on the limbs, there is a tendency to favor as extensive a surgery as possible. It seems that the larger the excision, the cleaner it becomes, which helps to prevent future recurrence and metastasis. Even undergoing amputation surgery doesn’t necessarily eliminate the risk of metastasis and recurrence. Sometimes, if the margins of the excision are not beyond the range, the risk still exists. Therefore, the extent of the excision should be determined based on the patient’s condition.