Melanoma, also known as malignant melanoma, originates from the malignant transformation of melanocytes. It is commonly found in individuals with fair skin, blond or red hair, and blue eyes, who are often prone to this type of disease, particularly in tropical regions where the condition is more prevalent. The incidence rate increases after the age of fifty, and the rate of occurrence between men and women within the same group is quite similar. In a minority of cases, melanoma can also occur in parts outside of the skin, such as the anus, rectum, esophagus, or inside the eyes. When the tumor is confined within the epidermis, referred to as in situ carcinoma, it can be cured through surgery. If there is metastasis, treatment may include immunotherapy, chemotherapy, or local radiotherapy.