Is genital herpes serology accurate?

Written by Luo Hong
Dermatology Department
Updated on September 03, 2024
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Serological testing for genital herpes in hospitals generally provides testing for type 1 and type 2 viruses, including IgM and IgG. Over 90% of genital herpes cases are primarily caused by type 2 virus, so the focus is typically on type 2 virus IgG and IgM. However, IgM represents an active infection, meaning a current infection stage. If IgM is negative and IgG is positive, it indicates a past infection. These results are generally accurate, but their timeliness is not as high as DNA's timeliness. Therefore, if possible, it is best to collect vesicle fluid on the first or second day of a herpes outbreak and use PCR to test the DNA for the most accurate results.

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Written by Zhai Yu Juan
Dermatology Department
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Can people with genital herpes eat seafood?

Genital herpes is a sexually transmitted disease caused by herpes simplex virus infection. The transmission routes mainly include sexual contact, close living contact, and mother-to-child transmission. Clinically, genital herpes primarily presents as clusters of erythema and blisters on the external genitals, with local burning and stabbing sensations. Initial outbreaks of genital herpes may include significant systemic symptoms such as fatigue and fever. After diagnosing genital herpes, antiviral medications like acyclovir are the first choice. In terms of diet, it is necessary to avoid spicy and irritating foods, pay attention to rest, and enhance immunity. Eating seafood is not a problem and does not affect the recovery and prognosis of genital herpes.

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Written by Xie Ming Feng
Dermatology
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How long is the incubation period for genital herpes?

The incubation period of genital herpes generally ranges from 2 to 14 days, with an average of 3 to 5 days, meaning that patients might not exhibit any symptoms during the incubation period. After this period, erythema can appear around the external genitalia, followed by the development of papules, vesicles, erosions, ulcers, and crusts, which may be accompanied by pain, burning sensations, and itching. The local lymph nodes may swell, and some patients may experience headaches, fever, and fatigue as systemic symptoms.

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Written by Luo Hong
Dermatology Department
48sec home-news-image

Is genital herpes serology accurate?

Serological testing for genital herpes in hospitals generally provides testing for type 1 and type 2 viruses, including IgM and IgG. Over 90% of genital herpes cases are primarily caused by type 2 virus, so the focus is typically on type 2 virus IgG and IgM. However, IgM represents an active infection, meaning a current infection stage. If IgM is negative and IgG is positive, it indicates a past infection. These results are generally accurate, but their timeliness is not as high as DNA's timeliness. Therefore, if possible, it is best to collect vesicle fluid on the first or second day of a herpes outbreak and use PCR to test the DNA for the most accurate results.

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Written by Xie Ming Feng
Dermatology
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What medicine is good for genital herpes?

For topical treatment of genital herpes, clinicians generally use antiviral medications such as acyclovir ointment, penciclovir cream, sodium phosphonoformate ointment, interferon ointment, and so on. If there is a concurrent bacterial infection, ointments like erythromycin, fusidic acid cream, and mupirocin ointment can be used in combination. Additionally, traditional Chinese medicine ointments that detoxify and dry dampness, such as borax and zinc oxide menthol ointment, can also be used.

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Written by Li Ya Ping
Dermatology Department
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What should I do if I get genital herpes?

Genital herpes is a type of sexually transmitted disease. If you contract genital herpes, first and foremost, you should avoid sexual contact to prevent transmitting it to others. Secondly, it’s important to rest and eat a light diet. Try to avoid smoking, drinking alcohol, or consuming particularly spicy foods, as these can also aid in recovery from the illness. Thirdly, treatment can include oral antiviral medications since genital herpes is an infection caused by the herpes simplex virus, mainly type 2. Therefore, antiviral medications such as acyclovir, valacyclovir, and famciclovir should be taken. Additionally, topical antiviral treatments, such as acyclovir ointment and penciclovir cream, can be used. If the blisters rupture and secondary infection occurs, antibiotic ointments like mupirocin should be applied to prevent further aggravation of the infection.