Can Crohn's disease be inherited by children?

Written by Ren Zheng Xin
Gastroenterology
Updated on September 18, 2024
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Crohn's disease is an inflammatory bowel condition, and its specific causes are not yet very clear. It may be related to environmental factors, lifestyle factors, dietary factors, and genetic factors, and it occurs more often in males than in females. The prevalence of Crohn's disease is relatively low in China. Typical symptoms of Crohn's disease include abdominal pain, diarrhea, intestinal obstruction, and some patients may experience fever, oral mucosal lesions, and liver abnormalities. The current treatment is mainly medication combined with surgical intervention. During active periods, it is important to rest, consume a low-fat, high-nutrition diet, replenish water and electrolytes timely, and if anemia is present, appropriately supplement with B12 and folic acid. Patients with hypoproteinemia should be given albumin.

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Written by Wu Hai Wu
Gastroenterology
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Crohn's disease daily diarrhea frequency

Crohn's disease can cause diarrhea, sometimes occurring two to three times a day, and in severe cases, it can happen dozens of times per day. The diarrhea caused by Crohn's disease may include mucus-like or pus-blood-like stool, and it is also accompanied by chills, fever, weight loss, etc. In severe cases of Crohn's disease, there is a possibility of intestinal perforation. Therefore, once Crohn's disease is diagnosed, aggressive treatment is necessary. Initially, drugs such as mesalazine can be considered for treatment. If the treatment is not effective, it may be necessary to consider using steroids or immunosuppressants. If necessary, biological treatments such as infliximab may be used. (Please follow medical advice regarding medication.)

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Written by Ren Zheng Xin
Gastroenterology
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Is Crohn's disease considered a serious illness?

Crohn's disease is a chronic condition and not considered a major illness. It involves inflammatory lesions of the intestines, often persists over a long duration, and tends to recur frequently without easy cure. It mainly affects the terminal ileum and the right half of the colon. Clinically, it presents symptoms such as diarrhea, abdominal pain, intestinal obstruction, and fever. It can also affect the liver, skin, and joints, with complications including acute perforation or rectal bleeding. Current treatment involves a combination of medication and surgery. Prompt surgical intervention is required in cases of complete intestinal obstruction, acute intestinal perforation, or substantial internal bleeding, and nutritional support should also be enhanced.

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Written by Si Li Li
Gastroenterology
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What is the difference between Crohn's disease and colitis?

Crohn's disease is a chronic nonspecific inflammatory disease, whose cause is currently unclear but may be related to immune mechanisms. Its main symptoms include abdominal pain, diarrhea, weight loss, and poor appetite. A colonoscopy can reveal longitudinal ulcers on the mucosa, distributed in segments. This disease has signs of lifelong recurrence, and currently, there are no specific effective medications, making treatment very challenging. The lesions can develop throughout the entire digestive tract. Chronic colitis primarily presents symptoms such as abdominal pain and diarrhea. A colonoscopy can show intestinal mucosal redness, swelling, and erosion. The condition generally responds well to treatment and is relatively milder compared to others.

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Written by Huang Gang
Gastroenterology
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Can Crohn's disease be inherited by the next generation?

The causes of Crohn's disease are not yet fully understood, but it is currently believed to be caused by the interaction of many factors, including environmental factors, genetic factors, infections, gut microbiota, and immune factors. The incidence of Crohn's disease in first-degree relatives of patients is significantly higher than in the general population. Therefore, it is considered that Crohn's disease is both a polygenic disease and a genetically heterogeneous disease. Individuals with genetic susceptibility may develop the disease under certain environmental influences. Thus, it appears that Crohn's disease has a certain genetic predisposition and can be inherited by the next generation. The typical symptoms of Crohn's disease include abdominal pain, diarrhea, and weight loss. Generally, the course of the disease progresses slowly, often presenting a chronic active phase alternating with remission, tends to be incurable, and has a lifelong tendency to recur. Currently, there is a lack of effective curative treatments for Crohn's disease. The primary approach is drug treatment to control the activity of the disease, maintain disease remission, prevent complications, and avoid intestinal damage.

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Written by Si Li Li
Gastroenterology
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What should Crohn's patients avoid eating?

Crohn's disease is a chronic non-specific inflammatory disease, the main symptoms of which include abdominal pain, diarrhea, weight loss, and abdominal masses. This disease is characterized by its difficult treatment, high propensity for relapse, and signs of lifelong recurrence. During colonoscopy, longitudinal and deep ulcers can be observed on the intestinal mucosa, which may indicate Crohn's disease, and these ulcers can appear throughout the gastrointestinal tract. Therefore, dietary precautions are essential. The diet should be easily digestible, and smoking and alcohol should be avoided. It is also advised to avoid strong tea, coffee, greasy, fried, barbecued, spicy, raw and cold foods, as well as sweets. It is preferable to consume porridge mainly, drink soup, or eat well-cooked noodles, and any type of meat should be thoroughly stewed before consumption.