If myasthenia gravis is well controlled, will it still recur?

Written by Shi De Quan
Neurology
Updated on May 12, 2025
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Myasthenia gravis is difficult to control, and even when controlled, it is prone to relapse. The characteristic of myasthenia gravis includes alleviation after rest, and a pattern of alternating episodes and remissions.

Since there is no etiological treatment for myasthenia gravis at present, most medications are symptomatic treatments. However, some patients can find relief through plasmapheresis or immunoglobulin therapy, but most patients will experience relapses.

Therefore, myasthenia gravis is a disease prone to relapse, and its recurrence is not greatly influenced by how well it is controlled; it depends on the specific circumstances.

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Written by Zhang Hui
Neurology
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Does myasthenia gravis require hospitalization?

Myasthenia Gravis is a type of neuroimmune disease within the field of neurology which fundamentally stems from issues with the patient's own immune function. Whether hospitalization is necessary depends critically on the severity of the disease. If Myasthenia Gravis manifests only as ocular symptoms, such as ptosis and double vision, hospitalization is generally not necessary. It is important to take certain medications, primarily cholinesterase inhibitors and corticosteroids, but regular outpatient follow-ups are essential. However, if Myasthenia Gravis is generalized, with noticeable whole-body weakness, particularly if accompanied by swallowing difficulties and coughing while drinking, hospitalization is required. If a myasthenic crisis occurs, presenting with respiratory muscle weakness and breathing difficulties, hospitalization is certainly needed, and admission to the ICU might be necessary.

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Written by Zhang Hui
Neurology
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Acupuncture treatment for myasthenia gravis

Patients with myasthenia gravis suffer from a systemic autoimmune disease, primarily affecting the neuromuscular junctions, which leads to corresponding clinical manifestations. The essence of the disease is caused by immune dysfunction, where the body produces specific antibodies that affect the transmission of impulses. Patients typically experience general weakness, double vision, drooping eyelids, and in severe cases, weakened respiratory muscles leading to respiratory paralysis. The treatment of myasthenia gravis mainly involves medication, including corticosteroids, immunoglobulins, acetylcholinesterase inhibitors, and other immunosuppressants. Additionally, there are some newer drugs that modulate the immune system. Acupuncture treatment, as an important method of traditional Chinese medicine, can also be used in the management of myasthenia gravis, primarily to improve the patients' resistance, enhance physical constitution, and play a significant role in preventing complications and reducing the dosage of other medications. (Specific medications should be administered under the guidance of a physician.)

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Written by Zhang Hui
Neurology
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The difference between amyotrophic lateral sclerosis and myasthenia gravis

These two are distinctly different diseases. Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease, which is a degenerative neurological condition primarily affecting the upper and lower motor neurons. Patients may exhibit symptoms such as muscle atrophy, muscle twitching, general weakness, as well as potential difficulties in swallowing, articulation disorders, and atrophy of the tongue muscles. The mechanism of this disease is not very clear, symptoms progressively worsen, and there are no effective treatment methods. Neurogenic changes can be observed in electromyography. Myasthenia gravis, on the other hand, is a typical neuromuscular junction disease caused by immune dysfunction. It presents with skeletal muscle fatigue and weakness, typically worsening in the evening. Treatment with immunosuppressants has been shown to be effective.

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Written by Zhang Hui
Neurology
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Types of Myasthenia Gravis Crisis

Myasthenia gravis is a neurological disease. It is an autoimmune disorder primarily affecting the neuromuscular junction, leading to symptoms such as pathological fatigue, ptosis, and limb weakness. Myasthenia gravis is termed as such due to its severe nature, including crises that can impair respiratory muscles, leading to respiratory paralysis, respiratory failure, and potentially death. There are three main types of myasthenic crises. The first type is myasthenic crisis, primarily caused by insufficient medication; muscular injections can be used for treatment, and if effective, it indicates a myasthenic crisis. The second type is called cholinergic crisis, resulting from an overdose of acetylcholinesterase inhibitors, with symptoms including muscular twitching and pupil constriction. The third type is called refractory crisis, occurring when the body is insensitive to medication treatments. All these crises pose a life-threatening risk to patients and require immediate management, including tracheal intubation and, if necessary, mechanical ventilation.

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Written by Shi De Quan
Neurology
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If myasthenia gravis is well controlled, will it still recur?

Myasthenia gravis is difficult to control, and even when controlled, it is prone to relapse. The characteristic of myasthenia gravis includes alleviation after rest, and a pattern of alternating episodes and remissions. Since there is no etiological treatment for myasthenia gravis at present, most medications are symptomatic treatments. However, some patients can find relief through plasmapheresis or immunoglobulin therapy, but most patients will experience relapses. Therefore, myasthenia gravis is a disease prone to relapse, and its recurrence is not greatly influenced by how well it is controlled; it depends on the specific circumstances.