Myasthenic crisis includes

Written by Zhang Hui
Neurology
Updated on April 23, 2025
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Myasthenia Gravis, a type of immune inflammatory disease of the nervous system, is mainly caused by the production of abnormal antibodies in the body. Myasthenic crisis can endanger the life safety of patients, affecting respiratory function. There are mainly three types of crises: The first type of crisis is the myasthenic crisis, which is also the most common. Generally, it is caused by the progression of the disease itself, often due to insufficient anticholinesterase drug dosage.

The second type of crisis is the cholinergic crisis, caused by an overdose of anticholinesterase drugs, resulting in symptoms like muscle tremors in patients.

The third type is the paradoxical crisis, which occurs due to insensitivity to anticholinesterase drugs, leading to severe respiratory difficulties. It is essential to handle a myasthenic crisis promptly, maintain the patient's airway clearance, and use a ventilator for treatment if necessary.

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Written by Liu Hong Mei
Neurology
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Can myasthenia gravis use non-invasive ventilators?

Myasthenia gravis can be treated with a non-invasive ventilator, and it is generally manageable with medication. Early stages of myasthenia gravis may present with symptoms such as ptosis, poor breathability, respiratory difficulty, worsening symptoms after activity, and increased severity in the evening. Respiratory weakness might require treatment with a non-invasive ventilator. If respiratory weakness does not improve with medication and leads to respiratory failure, it is advisable to use a non-invasive ventilator to improve the patient's symptoms and alleviate difficulties. Respiratory muscle weakness can be life-threatening and requires active treatment.

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Written by Liu Hong Mei
Neurology
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Is myasthenia gravis an autoimmune disease?

Myasthenia gravis is an autoimmune disease that primarily affects the neuromuscular junction, leading to abnormalities in acetylcholine receptors. This can cause weakness in some or all skeletal muscles, which easily fatigues, particularly after activity or exertion, with symptoms worsening. Symptoms can be alleviated after rest or treatment with cholinesterase inhibitors. As an autoimmune disease, myasthenia gravis often co-occurs with other autoimmune disorders such as hyperthyroidism, thyroiditis, systemic lupus erythematosus, and rheumatoid arthritis. Symptoms of myasthenia gravis typically lessen in the morning and worsen after activity, showing a pattern of being lighter in the morning and heavier in the evening.

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Written by Zhang Hui
Neurology
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incidence of myasthenia gravis

Myasthenia gravis is a disease of the neurology department. Its incidence rate is around one in one hundred thousand. The prevalence rate is around fifty per one hundred thousand. In China, the incidence rate in the south is slightly higher than in the north. This is an autoimmune disease of the nervous system. Generally, it is due to the production of some abnormal antibodies. These antibodies cause dysfunction in synaptic transmission at the neuromuscular junction, leading to corresponding clinical manifestations in patients. For example, extreme fatigue after physical activity that can only be alleviated by rest. Patients may also exhibit clinical symptoms such as ptosis, diplopia, and difficulty swallowing, and in severe cases, even respiratory muscle weakness may occur, requiring the use of a ventilator. This disease can occur at any age, affecting children as well as elderly men aged 70 to 80. Therefore, correct understanding of this disease and timely treatment are very important.

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Written by Zhang Hui
Neurology
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Myasthenia gravis often co-occurs with which diseases?

Myasthenia gravis is a type of autoimmune disease of the nervous system, mainly caused by the production of abnormal antibodies in the body. These antibodies affect the acetylcholine receptors in the postsynaptic membrane, thereby impacting the transmission of nerve impulses at the neuromuscular junction. Being an autoimmune disease, myasthenia gravis usually coincides with the following conditions: The first major category is thymus diseases, with most patients experiencing thymic hyperplasia, and particularly, there may be cases of thymoma. If there is a thymoma, it is advised to undergo surgical treatment promptly. The second major category may involve hyperthyroidism, so it is essential to test thyroid function. Thirdly, some patients may also test positive for antinuclear antibodies, which requires careful differential diagnosis.

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What department is myasthenia gravis under?

Myasthenia gravis, this disease definitely requires registration with the Department of Neurology as it is a relatively common disease in neurology, and doctors in other departments are not particularly familiar with this disease, let alone diagnosis and treatment. Myasthenia gravis is an immune disease of the nervous system, and patients may experience generalized fatigue, which can be alleviated after rest. It is characterized by clinical symptoms that are lighter in the morning and more severe in the evening. Additionally, symptoms such as ptosis, double vision, and even some difficulties in swallowing and unclear speech, known as bulbar paralysis, may occur. This disease requires a thorough chest CT scan, as many patients have an associated thymoma. Furthermore, an electromyography examination is needed to check for antibodies related to myasthenia gravis, which is also important for guiding further treatment.