Can syphilis patients have children?

Written by Huang Ling Juan
Dermatology
Updated on May 15, 2025
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Syphilis patients can have children. After regular treatment, syphilis patients can conceive and bear children normally. After being treated for syphilis, the RPR test can become negative, indicating that there are no live syphilis spirochetes in the body and no infectivity. At this point, pregnancy is not affected. Some pregnant women, after treatment, can block mother-to-child transmission and prevent the spread of syphilis, which is a systemic sexually transmitted disease caused by infection with the syphilis spirochete. If a woman infected with syphilis becomes pregnant without undergoing standard syphilis treatment, the syphilis spirochete can infect the fetus through the placenta, leading to fetal disease. Some may experience stillbirth, miscarriage, premature birth, or even the birth of a child with congenital syphilis. Therefore, it is recommended that syphilis patients undergo standard treatment to cure syphilis before becoming pregnant.

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Written by Cui Lin Jing
Dermatology
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What are the symptoms of tertiary syphilis?

Tertiary syphilis mainly occurs two to three years, or even five to ten years or longer, after infection. The primary skin manifestations are gummas, which often occur on the extensor side of the lower legs, and can present as ulcerations, erosions, nodules, and hyperplasia. It may also involve bones, joints, the heart, and blood vessels. The main manifestations include aortitis, aortic valve insufficiency, and aortic aneurysms. When the nervous system is involved, it can present as spinal tuberculosis and general paralysis, which are symptoms of paralytic dementia. The diagnosis of tertiary syphilis requires serological tests and cerebrospinal fluid analysis. The treatment involves primarily penicillin and benzathine penicillin, with erythromycin or tetracycline as alternatives for patients allergic to penicillin, and requires a longer course of treatment.

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Written by Zhu Zhu
Dermatology
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Can third-stage syphilis still be cured?

Third-stage syphilis can still possibly be cured, but this varies from person to person and is not absolute. Usually, when syphilis develops to the third stage, it indicates a more severe infection and is considered late-stage. Additionally, third-stage syphilis is particularly prone to causing cardiovascular, neurological, and musculoskeletal damages, which are complications. Therefore, treating third-stage syphilis is much more challenging compared to the first and second stages. It is crucial to treat and diagnose it early.

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Written by Luo Hong
Dermatology Department
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Gonorrhea and syphilis symptoms

Gonorrhea infection, if in males, generally presents with significant urethral irritation including symptoms such as urethral discharge, frequent urination, urgent urination, and pain during urination. However, in females with gonorrhea, it may cause increased vaginal discharge and an unusual odor, but many women with gonorrhea do not exhibit any symptoms. As for syphilis, if it is primary syphilis, ulcers may appear on the genitals, lips, or other body parts, known as chancres. In typical secondary syphilis, pinkish-red rashes may appear on the palms of the hands and soles of the feet, usually without itching, although rashes may also occur on the trunk and might not be itchy. Additionally, many cases of syphilis remain latent and show no clear symptoms.

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Written by Zhang Jian Bo
Dermatology
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What are the early symptoms of syphilis?

Syphilis is divided into overt and latent syphilis. Latent syphilis, regardless of whether it is early or late stage, shows no symptoms at all and can only be confirmed by blood testing. The symptoms in the early stage are mainly those of overt syphilis, primarily manifestations of primary syphilis. The stages of primary, secondary, and tertiary syphilis begin with the appearance of a lesion at the site of infection, typically about 0.5 to 1 centimeter in diameter, with a hard, dark red nodule that feels like cartilage. The surface may have ulcers; it may be painless, or there may be no pain at all. Subsequently, nearby lymph nodes may become enlarged. This swelling of the lymph nodes is characterized by being painless, usually unilateral, with no redness or rupture. These are the clear symptoms of overt primary syphilis. If treated properly at this stage, recovery is generally rapid.

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Written by Xiong Hong Hai
Infectious Disease
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Which is more serious, syphilis or AIDS?

Syphilis and AIDS, between the two, AIDS is more serious. This is because AIDS currently cannot be cured, and requires long-term regular intake of antiretroviral drugs. Syphilis, on the other hand, can be completely cured. In the early stages of syphilis, such as primary and secondary syphilis, the treatment is often very effective and also very convenient. Generally, a treatment course of two to three weeks can cure most syphilis infections. Therefore, between syphilis and AIDS, AIDS is more serious. These two diseases often occur simultaneously because both are transmitted sexually.