Syphilis is a sexually transmitted disease caused by the infection of Treponema pallidum. The main transmission routes include sexual contact, mother-to-child transmission, close personal contact, and blood transmission. Once diagnosed with syphilis, formal treatment should be administered under the guidance of local doctors, with penicillin generally being the first choice for treatment. Both the patient and their sexual partners need to undergo thorough examination and treatment. Additionally, regular follow-up examinations are necessary after treatment, typically under the guidance of local doctors, with continuous follow-up for three years to ensure effective treatment of syphilis.