Can the eugenic five-item test detect syphilis?

Written by Kang Jian Hua

Reproductive Center

Updated on April 20, 2025

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To know whether the eugenic five-item test includes syphilis, it is first necessary to clarify the components of this test. The eugenic five-item test includes screenings for toxoplasmosis, rubella virus, cytomegalovirus, and herpes simplex virus types 1 and 2, and it does not include a test for syphilis. Therefore, the eugenic five-item test does not cover syphilis. These five tests are mainly aimed at checking for viral infections before or during early pregnancy. The presence of any of these infections can be harmful to the fetus, potentially leading to early miscarriage, stillbirth, or congenital malformations. Thus, the eugenic five-item test does not include a syphilis test, which falls under sexually transmitted disease screenings.

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Written by Zhu Zhu

Dermatology

1min 18sec

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Early symptoms of syphilis

Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum, with the disease course within two years referred to as early syphilis. Not all infected individuals display symptoms; asymptomatic syphilis is also known as latent syphilis. Symptomatic early syphilis primarily manifests as either primary or secondary syphilis. The main symptom of primary syphilis is a chancre, typically occurring as a clear-bordered ulcer in the genital area. It is flesh-colored and neither painful nor itchy. Several weeks after the chancre heals, secondary syphilis can develop, characterized by a rash that may resemble other skin conditions. Common manifestations include macules, papular macules, copper-red papules on hands and feet, flat condyloma, and syphilitic alopecia. Individuals who suspect they may have been exposed to syphilis should visit a hospital for a blood test to detect syphilis antibodies. Antibodies can usually be detected four weeks after infection, and a negative result three months later can rule out syphilis.

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Written by Zhu Zhu

Dermatology

29sec

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Can tertiary syphilis be transmitted to infants?

It is possible for a baby to be infected with third-stage syphilis. Third-stage syphilis is a late stage of the disease, and if a pregnant mother has third-stage syphilis, it is possible to transmit the disease to her baby through mother-to-child transmission during pregnancy and childbirth. Therefore, if you discover that you have syphilis, especially third-stage syphilis, it is crucial to receive treatment promptly to prevent transmitting it to the baby.

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Written by Zhai Yu Juan

Dermatology Department

38sec

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Is syphilis contagious?

Syphilis is a sexually transmitted disease caused by infection with the syphilis spirochete. After infection, the pathogen can invade various organs throughout the body, causing a variety of symptoms. As a classic sexually transmitted disease, syphilis is contagious, with its main routes of transmission being through sexual contact, mother-to-child transmission, and also through close contact, such as kissing, or the use of daily items from a syphilis patient, such as towels, razors, cutlery, etc. If syphilis is not treated, its infectivity gradually decreases over time.

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Written by Qu Jing

Dermatology

1min 58sec

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How long is the latency period of syphilis?

Syphilis is a chronic infectious disease caused by the bacterium Treponema pallidum (TP), primarily transmitted through sexual contact and blood. The impact of syphilis is significant as it can affect all bodily tissues and organs, or can be transmitted through the placenta, leading to stillbirth, miscarriage, premature birth, and congenital infections. When syphilis is suspected, due to its complex clinical manifestations, a detailed medical history should be taken, a thorough physical examination conducted, and repeated laboratory tests performed to ensure an early and accurate diagnosis. It is important to trace back to any unprotected sexual contacts within the last six weeks and to routinely screen the sexual partners of patients for syphilis as well. Syphilis is divided into three stages: The diagnosis of primary syphilis is mainly based on the history of exposure, the incubation period (six weeks), typical clinical manifestations, and laboratory tests, noting that a negative syphilis serology result alone should not exclude the diagnosis of syphilis. The diagnosis of secondary syphilis primarily relies on the history of exposure, typical clinical manifestations, especially skin and mucosal lesions, combined with laboratory tests. The diagnosis of tertiary syphilis is mainly based on the history of exposure, typical clinical manifestations, and laboratory tests. Neurosyphilis can also be assessed through cerebrospinal fluid examination. Congenital syphilis primarily requires a maternal history of the disease, combined with typical clinical manifestations and laboratory tests for diagnosis.

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Written by Kang Jian Hua

Reproductive Center

47sec

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Can the eugenic five-item test detect syphilis?

To know whether the eugenic five-item test includes syphilis, it is first necessary to clarify the components of this test. The eugenic five-item test includes screenings for toxoplasmosis, rubella virus, cytomegalovirus, and herpes simplex virus types 1 and 2, and it does not include a test for syphilis. Therefore, the eugenic five-item test does not cover syphilis. These five tests are mainly aimed at checking for viral infections before or during early pregnancy. The presence of any of these infections can be harmful to the fetus, potentially leading to early miscarriage, stillbirth, or congenital malformations. Thus, the eugenic five-item test does not include a syphilis test, which falls under sexually transmitted disease screenings.