Can a routine blood test detect syphilis?

Written by Fu Ye Song

Hematology

Updated on September 16, 2024

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Syphilis is a contagious disease, and we cannot detect syphilis through routine blood tests, as these tests only measure elements such as the number of white blood cells, red blood cells, and platelets in the blood. Since syphilis is caused by an infectious agent, it cannot be detected through routine blood tests. It can only be detected by checking for antibodies using methods like ELISA immunofluorescence. Therefore, routine blood tests cannot detect syphilis.

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Written by Qu Jing

Dermatology

1min 49sec

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What are the symptoms of syphilis?

Syphilis is divided into acquired syphilis and congenital syphilis, which is transmitted via the fetus. Acquired syphilis, based on the duration of the disease and using two years as a boundary, is further divided into early-stage syphilis and late-stage syphilis. Early-stage syphilis, particularly primary syphilis, mainly presents symptoms such as a chancre and scleradenitis, generally without systemic symptoms. Secondary syphilis occurs when primary syphilis is untreated or not completely treated, allowing the virus to enter the bloodstream from the lymphatic system and spread throughout the body. This causes damages to the skin, mucous membranes, and systemically, known as secondary syphilis. It can manifest as various forms of syphilitic rash, some resembling papular rashes, others similar to dermatitis, eczema, flat lichen, urticaria, psoriasis, pustular disease, and others. Some secondary syphilitic rashes are similar to flat genital warts, and sometimes syphilis can lead to alopecia. Syphilis can also affect mucous membranes, appearing in the mouth, tongue, pharynx, larynx, and genital mucous membranes, characterized by one or more areas of distinct erythema, vesicles, erosion, covered with a grayish-white membrane, generally painless. Some syphilis cases might affect bones, causing damage to bones and joints. Latent syphilis presents no obvious symptoms, and late-stage syphilis might involve the cardiovascular and nervous systems.

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Written by He Jing

Obstetrics and Gynecology

1min 5sec

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Is fungal vaginitis related to syphilis?

Yeast vaginitis and syphilis are unrelated. Yeast vaginitis is caused by a disruption in the vaginal environment leading to an infection with Candida albicans, resulting in increased vaginal discharge. This is accompanied by itching of the vulva and the discharge may appear like cottage cheese or have a curd-like texture. However, syphilis is caused by the infection of the bacterium Treponema pallidum. It is a sexually transmitted disease characterized primarily by painless ulcers on the genitals. The treatment methods for the two are also different. Yeast vaginitis can be treated by external washing with baking soda and inserting clotrimazole vaginal suppositories, typically resolving within about a week. Treatment for syphilis, on the other hand, generally involves intravenous injections of penicillin. (Medication use should be supervised by a professional doctor.)

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Written by Zhu Zhu

Dermatology

41sec

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Can third-stage syphilis be cured?

Third-stage syphilis can potentially be fatal, but this is not absolute. With proper and timely treatment, it can gradually improve. Third-stage syphilis is the most severe and latest stage of the disease, also known as late-stage syphilis. This stage often affects our skin, bones, cardiovascular system, and even the nervous system. When these systems are affected, corresponding complications can arise. If left untreated, late-stage complications can lead to death. However, if treated early, there is a possibility of cure over time.

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Written by Zhu Zhu

Dermatology

40sec

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Can third-stage syphilis be completely cured?

Whether tertiary syphilis can be completely cured depends on the specific conditions of different patients. If tertiary syphilis has not caused serious complications, then timely and standard syphilis treatment at this stage can potentially lead to a cure. However, if it has been a long time and the condition has been neglected, it might cause severe damage to tissue and organ functions and can be life-threatening. At this point, it cannot be completely cured; even using anti-inflammatory drugs to treat syphilis cannot reverse the complications and greatly affects the quality of life.

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Written by Zhai Yu Juan

Dermatology Department

1min 5sec

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Treatment of Syphilis

Syphilis is a sexually transmitted disease caused by infection with the syphilis spirochete. Transmission routes include sexual contact, mother-to-child transmission, close living contact transmission, and blood transmission. Sexual transmission is the main mode of transmission. After infection with syphilis, it can affect various organs throughout the body, causing a variety of symptoms. Syphilis is primarily diagnosed through hematological tests to determine if one is infected. After a diagnosis of syphilis, formal anti-syphilis treatment is needed, with the first choices being long-acting penicillin and benzathine penicillin. After treatment, regular follow-ups are necessary, generally over a three-year period: every three months in the first year, every six months in the second year, and once in the third year, to determine if the condition has improved. (Medication should be used under the guidance of a doctor.)