Can a routine blood test detect syphilis?

Written by Fu Ye Song

Hematology

Updated on September 16, 2024

00:00

00:00

Syphilis is a contagious disease, and we cannot detect syphilis through routine blood tests, as these tests only measure elements such as the number of white blood cells, red blood cells, and platelets in the blood. Since syphilis is caused by an infectious agent, it cannot be detected through routine blood tests. It can only be detected by checking for antibodies using methods like ELISA immunofluorescence. Therefore, routine blood tests cannot detect syphilis.

Other Voices

home-news-image

Written by Zhu Zhu

Dermatology

43sec

home-news-image

When is the third stage of syphilis?

Tertiary syphilis is a relatively late stage of syphilis, often occurring two to three years after the initial detection of the disease. For patients with a longer course of the disease, it generally appears five to ten years later. Once tertiary syphilis is diagnosed, it is often accompanied by damage to various organ functions, such as the cardiovascular system, bones, skin, and nervous system. Therefore, it is crucial to detect and treat syphilis early and to follow standard treatment protocols with a doctor. Otherwise, once it progresses to tertiary syphilis, it becomes very difficult to cure.

home-news-image

Written by Luo Hong

Dermatology Department

52sec

home-news-image

Can syphilis antibodies be detected during the hard chancre stage?

During the hard chancre phase of syphilis, a portion of cases can test positive for Treponema pallidum, although some tests may return negative results. In such cases, it is advisable to retest after one month. The earliest detectable antibodies for Treponema pallidum are usually of two types: a Treponema pallidum-specific antibody, which appears earlier than the non-specific antibodies. There are tests for non-specific antibodies, commonly referred to as RPR or TRUST, which are standard practices in major hospitals. Therefore, in early-stage syphilis or primary syphilis with hard chancre, it is possible to find Treponema pallidum-specific antibodies positive, RPR or TRUST negative, or both negative. If syphilis is strongly suspected in such cases, a retest is recommended after one month.

home-news-image

Written by Zhu Zhu

Dermatology

45sec

home-news-image

How long does it take to cure third-stage syphilis?

The healing time for third-stage syphilis varies from person to person. Third-stage syphilis is considered a late stage of the disease, and the situation is very serious for patients who have developed to this stage. Therefore, the duration of illness for most patients is usually very long; it could be several months or even years, which also depends on the patient's level of aggressive treatment and their own immune resistance. Additionally, it is necessary to consider complications of third-stage syphilis. If there are severe complications involving cardiovascular and nervous systems, or joint damage, recovery can be very prolonged and difficult.

home-news-image

Written by Zeng Zhong

Urology

37sec

home-news-image

Can urethritis syphilis recur?

Urethritis and syphilis can both recur. Urethritis is primarily due to bacterial cleansing, leading to inflammatory infection of the urinary tract. If personal hygiene is not maintained, it can cause recurrence of urethritis, or the presence of other urinary system diseases may also lead to its recurrence. A relapse of syphilis refers to the condition where, after treatment, the titer is controlled below 1:4, but during an intermittent observation period, the titer rises again, and the proportion of increase is relatively high. This situation is considered a recurrence of syphilis.

home-news-image

Written by Cui Lin Jing

Dermatology

1min 4sec

home-news-image

What are the symptoms of tertiary syphilis?

Tertiary syphilis mainly occurs two to three years, or even five to ten years or longer, after infection. The primary skin manifestations are gummas, which often occur on the extensor side of the lower legs, and can present as ulcerations, erosions, nodules, and hyperplasia. It may also involve bones, joints, the heart, and blood vessels. The main manifestations include aortitis, aortic valve insufficiency, and aortic aneurysms. When the nervous system is involved, it can present as spinal tuberculosis and general paralysis, which are symptoms of paralytic dementia. The diagnosis of tertiary syphilis requires serological tests and cerebrospinal fluid analysis. The treatment involves primarily penicillin and benzathine penicillin, with erythromycin or tetracycline as alternatives for patients allergic to penicillin, and requires a longer course of treatment.