Tetanus generally occurs how long after infection?

Written by Zhang Peng
General Surgery
Updated on May 08, 2025
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Tetanus infection generally has an incubation period, which largely depends on the location of the wound, the extent of infection, and the immune status of the body. This period is mostly about one week, but it can be as short as 24 hours and as long as several months or even years. For patients with shorter incubation periods, the symptoms tend to be more severe after the onset, and the prognosis is worse, with 90% of patients developing the disease within two weeks of injury. For neonatal tetanus infections, the typical incubation period is about a week after the umbilical cord has been cut, and occasionally, symptoms of tetanus can occur years later after the removal of a foreign body that had remained in the body. For tetanus infection, timely preventive vaccinations should be administered; the general principle is not to exceed 24 hours. Even if more than 24 hours have passed without the onset of the disease, timely vaccination can still achieve preventive effects.

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Written by Liu Huan Huan
General Surgery
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Can I get a tetanus shot in the evening?

If a patient has a relatively deep wound, such as reaching the subcutaneous fat layer or even more severely, the muscle layer, it is important to prevent tetanus infection. It is advised that the patient must come to the hospital for a tetanus antitoxin injection into the muscle. After an injury, the sooner the tetanus antitoxin is injected, the better, as delays can affect the effectiveness of the antitoxin. Therefore, tetanus antitoxin can also be administered at night. Generally, one should go to the emergency surgery department of the hospital for the injection, as the emergency surgery department is on duty 24 hours a day, so it is possible to receive the tetanus shot at night.

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Written by Tang Da Wei
General Surgery
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Where is the tetanus shot given?

Tetanus injections require administration into the muscle, typically in the deltoid or gluteus maximus, which is below the patient's shoulder or on the buttocks. Before administering a tetanus shot, a skin test is usually performed. The test takes place on the inner side of the forearm, where 0.1ml of the solution is injected. Patients might experience some pain during the tetanus shot, but most can tolerate it. The tetanus shot effectively prevents tetanus infections, especially in cases where the wound is deep with a small surface area that can create anaerobic conditions conducive to the colonization and proliferation of Clostridium tetani, leading to tetanus infection. Vaccination can effectively prevent some serious diseases.

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Written by Tang Da Wei
General Surgery
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How long does a tetanus shot last?

Tetanus shot refers to the tetanus antitoxin, which is a form of passive immunity. This means that when a patient suffers from external injuries, such as wounds on the feet or hands, the drug injected to prevent infection by tetanus bacillus inside the wound is tetanus antitoxin. It generally maintains its effect in the patient's body for about a week. If the patient's wound inflammation is severe and there is a suspicion of tetanus infection, it is necessary to clean the wound. If required, another injection of tetanus antitoxin might be needed after a week. On the other hand, getting the tetanus vaccine, which is an active immunity, usually involves the DTP vaccine and generally lasts about ten years.

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Written by Li Jin Quan
General Surgery
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Can tetanus be cured?

In clinical practice, the vast majority of tetanus patients can be cured, provided there are no severe complications. Typically, tetanus is caused by the toxin produced by Clostridium tetani within the human body, leading to a specific type of infection. Clinically, it usually manifests as muscle tension and rigidity, and some patients might experience lockjaw, difficulty opening the mouth, a sardonic smile, and even stiff neck and opisthotonos. Severe cases can lead to difficulty breathing, respiratory arrest, or even cardiac arrest. Tetanus patients should go to the hospital for systematic, formal treatment and care. The vast majority of tetanus patients can be cured.

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Written by Zhang Peng
General Surgery
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What should I do if I drink alcohol with tetanus?

If there are high risk factors for tetanus infection after an injury, and alcohol has been consumed, it is generally advisable to wait until sobriety before conducting relevant skin tests. Currently, there is no clear research on the relationship between alcohol consumption and an allergy to tetanus antitoxin. It is not very clear whether alcohol impacts the results of a skin test, so it is safer to perform the test after sobering up. Since the consequences of a tetanus infection can be severe, and the tetanus injection itself carries a certain risk of anaphylactic shock, which can lead to multiple organ problems and even be life-threatening, it is generally safer to conduct the skin test after sobering up and then proceed with the timely injection treatment. If the skin test is positive, tetanus immunoglobulin should be chosen promptly.