Tetanus generally occurs how long after infection?

Written by Zhang Peng
General Surgery
Updated on May 08, 2025
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Tetanus infection generally has an incubation period, which largely depends on the location of the wound, the extent of infection, and the immune status of the body. This period is mostly about one week, but it can be as short as 24 hours and as long as several months or even years. For patients with shorter incubation periods, the symptoms tend to be more severe after the onset, and the prognosis is worse, with 90% of patients developing the disease within two weeks of injury. For neonatal tetanus infections, the typical incubation period is about a week after the umbilical cord has been cut, and occasionally, symptoms of tetanus can occur years later after the removal of a foreign body that had remained in the body. For tetanus infection, timely preventive vaccinations should be administered; the general principle is not to exceed 24 hours. Even if more than 24 hours have passed without the onset of the disease, timely vaccination can still achieve preventive effects.

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Written by Zhang Peng
General Surgery
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When is the best time to get a tetanus shot?

Tetanus infection carries a certain mortality rate, with current statistics indicating that the death rate from tetanus infection can reach around 40%. Typically, tetanus is caused by an acute, specific infection resulting from the growth and reproduction of Clostridium tetani in human wounds, which produce toxins. Generally, it can only grow and reproduce in an anoxic environment, so it is most commonly found in soil, human and animal feces, and rust. For wounds, especially sharp and deep cuts, it is usually vital to administer a tetanus shot promptly. The choices generally are tetanus immunoglobulin or tetanus antitoxin, which have different half-lives; tetanus antitoxin generally lasts about three days, whereas tetanus immunoglobulin can last up to three weeks. Therefore, in the presence of high-risk infection factors, it is advisable to administer the injection as soon as possible, generally recommended within 24 hours.

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Written by Gao Sen
General Surgery
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Tetanus 0.1ml how many units

In general, the dose of tetanus toxoid is 1500 international units per dose, approximately 1 ml per dose, and generally about 150 international units per 0.1 ml, which can be referred to the instructions. The use of tetanus toxoid should be avoided blindly and should be administered under the guidance of a physician. Additionally, wound cleaning and disinfection should be performed before administering tetanus toxoid. Furthermore, anti-infection treatment should be considered based on the contamination of the wound.

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Written by Liu Huan Huan
General Surgery
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Do you need a tetanus shot for a scraped skin?

Tetanus bacterial infection generally refers to relatively deeper wounds. A deeper wound creates an anaerobic environment locally, where tetanus-causing bacteria can reproduce and grow, leading to infection. If the wound is just a scrape and not deep, it's less likely to form an anaerobic environment. In such cases, the likelihood of developing tetanus is extremely low. From personal experience, if it's just a minor scrape, simply disinfecting the area with iodine is sufficient; there is generally no need for a tetanus antitoxin injection.

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Written by Xing Wen Jun
General Surgery
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Where is the tetanus shot injected?

Tetanus antitoxin is generally administered via intramuscular injection, commonly in the buttock muscles. If a patient is injured by a rusty iron object, and the wound is small and deep, it is generally recommended to consider administering tetanus antitoxin actively within 24 hours after the injury to help prevent tetanus. Additionally, for local wound care, the patient needs to rinse the wound with soap and water under running water, then clean, apply, rinse, and dry with hydrogen peroxide before disinfecting with iodine. Afterwards, covering the wound with sterile Vaseline gauze and sterile dressings is appropriate. Furthermore, the patient should keep the wound dry for up to three weeks after the injury as getting it wet may delay healing or increase the risk of incisional infection. Moreover, the patient should avoid alcohol and minimize the intake of spicy and irritating foods within a month after the injury.

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Written by Li Jin Quan
General Surgery
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How much is the tetanus serum?

When there is a potential risk of tetanus infection in our wounds, we should promptly receive a tetanus shot. The tetanus treatments commonly used today include tetanus antitoxin and tetanus immunoglobulin, also known as tetanus serum. Generally, the price of tetanus antitoxin is about seven to eight yuan each. Tetanus serum can be divided into two types: human tetanus immunoglobulin and horse tetanus immunoglobulin. The price of human tetanus immunoglobulin is slightly over 80 yuan, while horse tetanus immunoglobulin costs slightly over 30 yuan. Horse tetanus immunoglobulin requires a skin test before it can be administered.