Tetanus injections require administration into the muscle, typically in the deltoid or gluteus maximus, which is below the patient's shoulder or on the buttocks. Before administering a tetanus shot, a skin test is usually performed. The test takes place on the inner side of the forearm, where 0.1ml of the solution is injected. Patients might experience some pain during the tetanus shot, but most can tolerate it. The tetanus shot effectively prevents tetanus infections, especially in cases where the wound is deep with a small surface area that can create anaerobic conditions conducive to the colonization and proliferation of Clostridium tetani, leading to tetanus infection. Vaccination can effectively prevent some serious diseases.