Current research indicates that lactating women are not contraindicated for tetanus vaccination; the main contraindication is allergy to the tetanus vaccine. Generally, if there are high-risk factors for tetanus infection, timely wound debridement and care should be performed, followed by early administration of passive immunization with tetanus vaccine. Generally, tetanus antitoxin can be used based on the results of a skin test. If the skin test result is strongly positive, its use should be avoided, and tetanus immunoglobulin should be chosen instead. The effective metabolic period of tetanus immunoglobulin is about three weeks. If high-risk factors for infection still exist beyond this time limit, timely enhancement of immune therapy should be considered. Regarding the tetanus vaccine, it is generally advised that the earlier it is administered, the better, as early administration can neutralize the tetanus toxin already present in the blood. However, if the tetanus toxin has already bound to nerve cells, treatment becomes relatively difficult.