Tetanus allergic symptoms

Written by Li Jin Quan
General Surgery
Updated on September 05, 2024
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The primary allergic reaction to tetanus is anaphylactic shock. Some patients may experience skin redness, itching, chest tightness, difficulty breathing, pale complexion, and cold sweats within minutes after receiving the tetanus vaccine. Some may also experience nausea, vomiting, and even abdominal pain. Additionally, blood pressure may drop, and the pulse may slow down. In severe cases, coma can occur, and even cessation of heartbeat and breathing. The second type of allergic reaction is serum sickness, which can occur after a tetanus injection, characterized by erythema, edema, and itching at the injection site.

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How to administer a tetanus shot: steps

First, an allergy test must be conducted. Based on the results of the allergy test, the application of tetanus antitoxin is decided. The allergy test involves drawing 0.1 ml of antitoxin serum, diluting it with 0.9 ml of isotonic saline, and then injecting 0.05 to 0.1 ml of the diluted solution intradermally on the flexor side of the forearm. An equivalent amount of isotonic saline is injected on the other forearm as a control. Observe for 15-30 minutes. If there is no nodule or resistance at the injection site, it is a negative result. Patients with a negative result can have the rest of the original liquid injected subcutaneously. If a red nodule of about one centimeter or resistance appears at the serum injection site, the allergy test is positive. In this case, a desensitization injection is needed. The desensitization injection involves diluting the required injection fluid and the antitoxin serum with isotonic saline to ten times the volume and administering it subcutaneously in divided doses. After dilution to ten times the volume, which is 10 ml, the initial dose of 1 ml is administered, followed by 2 ml, 3 ml, and 4 ml, with each injection spaced 30 minutes apart until completed.

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Which department do I go to for a tetanus shot?

Tetanus shots are widely used clinically, and patients generally receive the injection after sustaining an injury. Therefore, it is recommended that patients visit the surgical department. If at a community hospital, they should go to the surgical outpatient clinic. If in a secondary or tertiary hospital, patients can go to the surgical outpatient clinic or the emergency surgery department for treatment. After wound treatment, they can receive a tetanus shot as required. Thus, patients usually go to the surgical department or emergency surgery for the tetanus injection.

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Is it necessary to get a tetanus shot?

Getting a tetanus shot is very necessary if a patient has had an injury or has wounds on the body. Without a tetanus shot, there might be a risk of tetanus infection. The main reason is due to the presence of tetanus bacillus spores in the natural environment, which could colonize within the wound if it's exposed. This can potentially lead to a tetanus infection. Severe cases can present with symptoms such as opisthotonos, breathing difficulties, suffocation, and could even lead to death. The tetanus shot involves injecting tetanus antitoxin into the patient's body, which is a form of passive immunity and can prevent some symptoms of tetanus infection.

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The likelihood of a wound being infected with tetanus

Tetanus is a specific infection often associated with trauma, with a high contamination rate of tetanus bacillus in traumatic wounds. On the battlefield, the contamination rate can reach 25% to 80%, although the incidence of tetanus in contaminated wounds is only about 10% to 20%. This suggests that other factors are necessary for the disease to occur, with the main factor being an anaerobic environment. If the wound is deep, with a small external opening, and contains necrotic tissue, blood clots, or is too tightly packed, this can lead to local ischemia. Additionally, if there is a co-infection with aerobic bacteria consuming residual oxygen in the wound, it creates an anaerobic environment conducive to the growth of the bacteria, thus increasing the likelihood of tetanus infection in the wound.

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Can tetanus be cured?

Tetanus is a curable disease. It is usually caused by an infection with the tetanus bacillus, which produces a specific infection in the human body. Clinically, it is mainly manifested as muscle tension and rigidity, with the primary symptoms being difficulty opening the mouth, a sardonic smile, neck stiffness, and opisthotonos. In severe cases, it can lead to respiratory confusion, respiratory arrest, or cardiac arrest. Therefore, patients with tetanus should go to the hospital for treatment as soon as possible. With standardized and systematic treatment, the vast majority of patients can be cured.