How long does a tetanus shot last?

Written by Xu Jun Hui
General Surgery
Updated on November 21, 2024
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After receiving a tetanus shot, it generally lasts for about six months. However, if you are injured again after six months and the wound is heavily contaminated, such as with contaminated soil or rust, and the wound is large and deep, it is advised to undergo tetanus treatment again. The purpose of the tetanus shot is to prevent infection by Clostridium tetani, which is an anaerobic bacterium. It tends to proliferate in anaerobic environments and in conditions of heavy contamination by rust and soil. Therefore, if after tetanus treatment the injury is relatively minor, shallow, and comparatively clean, it is sufficient to clean and dress the wound and keep it dry. If the wound is heavily contaminated, large, and deep, it is recommended to administer the tetanus shot again.

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How long does tetanus antibody last?

The duration of tetanus antibodies varies under two scenarios. The first is passive immunity, which is achieved through injections such as tetanus antitoxin or tetanus immunoglobulin. The duration of immunity provided by these injections is relatively short. Typically, tetanus antitoxin lasts about four days, while tetanus immunoglobulin can last up to three weeks. After this period, the levels of antibodies gradually decrease, and the body may no longer be protected. Therefore, a single application of tetanus antitoxin or immunoglobulin does not provide long-lasting immunity. The second scenario involves antibodies produced by active immunity, generally through the injection of a vaccine made from attenuated tetanus bacilli. Antibodies usually start to develop about ten days after vaccination, with levels gradually increasing over two to three months and remaining high. This type of immunity lasts up to about ten years, but it is not lifelong. Regular boosters, guided by relevant tests, are required to maintain immunity.

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Where is the tetanus shot injected?

Tetanus antitoxin is generally administered via intramuscular injection, commonly in the buttock muscles. If a patient is injured by a rusty iron object, and the wound is small and deep, it is generally recommended to consider administering tetanus antitoxin actively within 24 hours after the injury to help prevent tetanus. Additionally, for local wound care, the patient needs to rinse the wound with soap and water under running water, then clean, apply, rinse, and dry with hydrogen peroxide before disinfecting with iodine. Afterwards, covering the wound with sterile Vaseline gauze and sterile dressings is appropriate. Furthermore, the patient should keep the wound dry for up to three weeks after the injury as getting it wet may delay healing or increase the risk of incisional infection. Moreover, the patient should avoid alcohol and minimize the intake of spicy and irritating foods within a month after the injury.

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How to administer a tetanus shot: steps

First, an allergy test must be conducted. Based on the results of the allergy test, the application of tetanus antitoxin is decided. The allergy test involves drawing 0.1 ml of antitoxin serum, diluting it with 0.9 ml of isotonic saline, and then injecting 0.05 to 0.1 ml of the diluted solution intradermally on the flexor side of the forearm. An equivalent amount of isotonic saline is injected on the other forearm as a control. Observe for 15-30 minutes. If there is no nodule or resistance at the injection site, it is a negative result. Patients with a negative result can have the rest of the original liquid injected subcutaneously. If a red nodule of about one centimeter or resistance appears at the serum injection site, the allergy test is positive. In this case, a desensitization injection is needed. The desensitization injection involves diluting the required injection fluid and the antitoxin serum with isotonic saline to ten times the volume and administering it subcutaneously in divided doses. After dilution to ten times the volume, which is 10 ml, the initial dose of 1 ml is administered, followed by 2 ml, 3 ml, and 4 ml, with each injection spaced 30 minutes apart until completed.

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How to treat tetanus?

Generally speaking, a tetanus shot needs to be administered intramuscularly, but a skin test must be conducted before injection because tetanus vaccines can easily cause allergic reactions. The skin test usually involves a subcutaneous injection on the palm side of the forearm, followed by an observation period of 15 to 20 minutes. If there is no redness or itching, and the skin test is negative, then the vaccine can be administered intramuscularly, usually in the buttock. However, if the skin test is positive, as indicated by symptoms like redness, significant itching, or even systemic symptoms such as dizziness and cold sweats, it shows that the skin test for tetanus is positive. In this case, one can opt for a desensitization injection of diluted tetanus vaccine, followed by intramuscular injections four times, once every half hour, needing about two hours to complete.

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Does tetanus infect others?

Tetanus occurs when wounds are contaminated by Clostridium tetani, which then proliferates and grows within the human body, ultimately causing tetanus. Generally, tetanus is not transmitted from person to person; it usually occurs when bacteria invade the body through external injuries or wounds. Additionally, newborns may contract tetanus through the birth canal during delivery. Therefore, for deep or large wounds, especially in heavily contaminated conditions, it is crucial to clean and possibly stitch the wounds promptly. If necessary, tetanus immune globulin injections and vaccinations against these bacteria can be administered to thoroughly prevent the occurrence of tetanus.