How long does it take for tetanus to develop?

Written by Ma Xian Shi
General Surgery
Updated on January 24, 2025
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Tetanus is an acute, specific infection caused by the invasion of Clostridium tetani into a human wound, where it grows and reproduces, producing toxins. Tetanus is a Gram-positive, anaerobic, spore-forming bacillus that is widely present in the external environment. Tetanus occurs only when tetanus bacillus grows and reproduces locally in a wound and produces exotoxins, which are the cause of the disease. The toxins of tetanus include spasm toxin and hemolysin. The incubation period of tetanus generally ranges from six to ten days. In some cases, it can occur within 24 hours or take as long as 20 to 30 days, or even months, particularly following the removal of foreign bodies or shrapnel. Neonatal tetanus generally occurs seven days after umbilical cord separation, clinically also known as the "seven-day wind." Generally, the shorter the duration of the incubation period or prodromal symptoms, the more severe the symptoms and the higher the mortality rate.

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Written by Zhang Peng
General Surgery
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How long do you have to get a tetanus shot?

It is generally recommended to receive an injection as soon as possible after a trauma, ideally within 24 hours, because tetanus has a certain incubation period, with the shortest being able to cause disease within 24 hours. There is still value in receiving the injection after 24 hours; it can alleviate symptoms and play a preventive treatment role. For tetanus, it is usual to administer a tetanus shot, and most people can choose between tetanus antitoxin or tetanus immunoglobulin. The duration of these two drugs is not the same; tetanus antitoxin lasts about three days, while tetanus immunoglobulin can last up to three weeks. However, this is not an absolute conclusion. Beyond this time, if there are high-risk factors for reinfection, a repeat injection is needed. If a patient has previously been protected by an active immunization regimen, in most cases, no special preventive treatment is needed within three years of the last vaccination.

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Written by Li Jin Quan
General Surgery
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Is tetanus serious?

In usual circumstances, when we diagnose tetanus, it is crucial to use a large amount of tetanus antitoxin and tetanus immunoglobulin early on to neutralize the toxins in the blood and alleviate the symptoms of tetanus. If tetanus severely manifests with symptoms such as muscle spasms, muscle rigidity, difficulty in opening the mouth, stiff neck, or complications like respiratory difficulty, respiratory failure, or even cessation of breathing and heartbeat, the condition can lead to severe complications and high mortality rates. Thus, tetanus becomes very severe in its late stages.

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Written by Li Jin Quan
General Surgery
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How long is a tetanus shot effective?

Tetanus generally refers to a specific type of infection caused by the entry of tetanus bacillus into the body through broken skin or mucous membranes, where it produces a large amount of toxin. Typically, the incubation period for tetanus is 6 to 7 days, but it can be as short as within 24 hours or as long as several months or even years. Therefore, if there is a wound, the first thing to do is to clean the wound with hydrogen peroxide or saline. Then, it is best to go to the hospital to get a tetanus vaccine within 24 hours. If the tetanus vaccine is not administered within 24 hours, it can still be effective if given within a week.

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Written by Ai Bing Quan
General Surgery
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Tetanus vaccination is effective if administered within a few days.

A tetanus shot is best administered within 24 hours after injury, and it is still effective if given within 48 hours. If not feasible, the injection can be administered within a week. Tetanus is caused by an infection with tetanus bacillus and is usually very severe. The incubation period for tetanus bacillus is about one week, hence, tetanus antitoxin should be administered as soon as possible after injury to prevent infection. If a tetanus antitoxin skin test is positive, tetanus immunoglobulin can be administered for immunologic skin testing. Symptoms of tetanus, when they appear, mainly include trismus, a forced grin, throat swelling, choking, opisthotonus, etc. If not promptly treated, these symptoms can lead to death.

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Written by Liu Huan Huan
General Surgery
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Do you need a tetanus shot for a scraped skin?

Tetanus bacterial infection generally refers to relatively deeper wounds. A deeper wound creates an anaerobic environment locally, where tetanus-causing bacteria can reproduce and grow, leading to infection. If the wound is just a scrape and not deep, it's less likely to form an anaerobic environment. In such cases, the likelihood of developing tetanus is extremely low. From personal experience, if it's just a minor scrape, simply disinfecting the area with iodine is sufficient; there is generally no need for a tetanus antitoxin injection.