The difference between pertussis and allergic cough

Written by Tong Peng
Pediatrics
Updated on November 16, 2024
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Pertussis (whooping cough) and allergic cough are different. Firstly, pertussis is an acute respiratory infectious disease caused by Bordetella pertussis. Its symptoms include paroxysmal and frequent coughing, sometimes accompanied by a deep, crowing, inspiratory whoop sound. If not treated promptly, the condition can last for several months, which is why it is called whooping cough. Due to its high contagiosity and epidemic history, if infants contract pertussis, their condition can worsen, making them prone to complications like severe pneumonia or heart failure. However, allergic cough is a non-infectious condition primarily caused by hypersensitivity of the airways, easily triggered by various external allergens, leading to irritating dry coughs, but not worsening to lower respiratory tract infections. In daily life, by avoiding environmental allergens and using treatments such as nebulization and oral antiallergic medications, management is possible.

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What are the symptoms of whooping cough?

Pertussis, a disease caused by infection with the Bordetella pertussis or Corynebacterium diphtheriae, is a contagious respiratory illness. The typical symptom is severe coughing, which presents as paroxysmal, rapid coughing fits. This coughing can lead to redness in the face and ears, a runny nose, tears, and bulging neck veins. If these coughing symptoms are prolonged, it is advisable to visit a hospital to check the pathogen in the secretions. Once the pathogen is confirmed, treatment can include oral or intravenous macrolide antibiotics to control the infection, along with symptomatic treatment. (Note: The use of medications should be under the guidance of a professional doctor.)

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Pertussis and measles transmission pathways

Pertussis and measles are two types of diseases, both of which are respiratory infectious diseases. Pertussis is caused by Corynebacterium diphtheriae or Bordetella pertussis, while measles is an acute, infectious disease caused by the measles virus. Transmission mainly occurs through close contact with infected individuals and via airborne droplets, and it is commonly seen in infants and young children under the age of five. Prevention of these diseases is primarily through vaccination, and once the disease occurs, it is important to promptly treat the infection with anti-inflammatory or antiviral treatments, while also managing the symptoms accordingly.

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How to diagnose the incubation period of pertussis

The incubation period of whooping cough generally has no autonomous discomfort symptoms. If there is close contact with a patient and the body lacks antibodies, suspecting the presence of this pathogen, corresponding auxiliary examinations can be conducted for diagnosis. Bacteriological examinations and fluorescent antibody methods can be performed, using nasopharyngeal swab secretions smear or nasal mucosa impression smear fluorescent antibody staining to detect specific antigens, with an early positive rate of 75%-85%. Complement fixation tests in serology can also be conducted to detect specific antibodies, effectively aiding in the diagnosis of atypical cases.

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The "hundred days" in whooping cough refers to what?

The whooping cough we refer to clinically is a type of respiratory infectious disease. The term "hundred days" relates to the duration of the disease, which is relatively long, sometimes approaching one hundred days, hence the name whooping cough. However, it does not necessarily mean that one will cough or be infected for such a long duration. The specific circumstances should be determined according to the number of infecting pathogens and the body's immune response. If the immune system is normal and the infection is minor, some patients can recover without medication. Once a severe infection is diagnosed, it is crucial to promptly use sensitive antibiotics and engage in timely anti-inflammatory and symptomatic treatment.

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Is the pertussis vaccine an inactivated vaccine?

The pertussis vaccine is not an inactivated vaccine but a live attenuated vaccine, which primarily stimulates the body to produce antibodies. Once antibodies are produced, it can effectively prevent the disease pertussis. The commonly used pertussis vaccine in clinical settings is the trivalent vaccine, also known as the DTP vaccine, which can prevent pertussis, diphtheria, and tetanus—three infectious diseases caused by pathogens. It is essential to follow medical advice and complete the vaccination schedule as prescribed to achieve prevention. After vaccination, it is crucial to observe for any complications or adverse reactions.