The "hundred days" in whooping cough refers to what?

Written by Li Jian Wu
Pulmonology
Updated on April 17, 2025
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The whooping cough we refer to clinically is a type of respiratory infectious disease. The term "hundred days" relates to the duration of the disease, which is relatively long, sometimes approaching one hundred days, hence the name whooping cough. However, it does not necessarily mean that one will cough or be infected for such a long duration. The specific circumstances should be determined according to the number of infecting pathogens and the body's immune response. If the immune system is normal and the infection is minor, some patients can recover without medication. Once a severe infection is diagnosed, it is crucial to promptly use sensitive antibiotics and engage in timely anti-inflammatory and symptomatic treatment.

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Written by Li Jian Wu
Pulmonology
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How long is the incubation period for whooping cough?

Once the body is infected with the bacterium that causes whooping cough, the incubation period of this disease is about one to two weeks. The contagion is strongest within two to three weeks after becoming ill. This disease is a respiratory infectious disease, mainly transmitted through airborne droplets, with children under five being the most susceptible to infection. Clinically, vaccination is primarily used to prevent the occurrence of the disease. Once infected, symptomatic treatment is needed, and one can also choose macrolide antibiotics, such as clarithromycin and erythromycin, for treatment.

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Written by Zeng Hai Jiang
Pediatrics
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Why is whooping cough milder during the day and worse at night?

Whooping cough is an acute respiratory infectious disease caused by Bordetella pertussis infection, commonly seen in children. The main symptoms are paroxysmal spasmodic coughing, a crowing inspiratory noise, with coughing occurring both during the day and at night, more significantly at night. The main reasons are as follows: first, the dry indoor air causes irritation. Second, during the night, the mucus secreted by the bronchial mucosa cannot be expelled from the body, which stimulates the bronchial nerves and triggers worsening cough symptoms. Coughing can also cause redness of the face and ears, runny nose, nausea, and vomiting.

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Written by Li Jian Wu
Pulmonology
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How is whooping cough transmitted?

Pertussis, commonly known as whooping cough, is primarily caused by the infection of Bordetella pertussis. The main transmission routes are through the respiratory tract or via close contact, particularly in classrooms where young children are present, which can easily lead to cross-infection. The disease has an incubation period of about three to seven days, and in some cases, it can range from two to three weeks. Children under the age of five have the highest incidence rate. Clinically, vaccination is recommended for prevention. Once infected, the early stages of the disease resemble those of a common cold, with typical symptoms being paroxysmal, spasmodic coughing.

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Written by Li Jian Wu
Pulmonology
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Whooping cough vaccine at what age?

The pertussis vaccine is generally administered within the first year of age. Under normal circumstances, children should be taken to hospitals or public health prevention stations for vaccination according to the course of treatment. The first dose starts at the third month after birth, followed by the second dose at four months and the third dose at five months old. A booster can be administered when the baby is two years old. The DTP vaccine used in clinics mainly consists of three components: pertussis, diphtheria, and tetanus.

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Written by Wu Ben Rong
Pediatrics
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What should I do if pertussis recurs a second time?

After recovering from whooping cough, patients usually produce antibodies in their bodies, so recurrences are rare. However, some patients may have weak constitutions, low immunity, and poor resistance. If they do not generate enough antibodies after being sick, they may get infected again when exposed to someone with whooping cough, leading to a second onset of the disease. If whooping cough recurs, the treatment plan is exactly the same as for the first occurrence, but patients should focus on boosting their immune system and resistance during treatment. In daily life, it is beneficial to eat foods rich in high-quality proteins and vitamins and to persist in physical exercise regularly.