The pertussis vaccine is a type of vaccine that must be administered, so it is essential to get it. Generally, the first dose is given when a baby is three months old, with the second and third doses administered at four and five months, respectively, completing one course of treatment. Between one and a half to two years old, a booster shot can be administered. If effective antibodies are produced, it can prevent pertussis. Clinically, this vaccine is mostly a combination vaccine that can prevent three diseases: diphtheria, pertussis, and tetanus.