The care for incontinence-associated dermatitis primarily involves keeping the affected skin clean and dry. It is important to avoid skin contact with urine as much as possible. If the skin does come into contact with urine, it should be washed promptly and kept clean and dry.

If there is itching or discomfort at the site of the dermatitis, topical corticosteroid ointments may be used to alleviate the itching. Some patients might also develop infections, typically bacterial, which can be managed with antibiotics. For patients with recurrent dermatitis, considering bladder fistulation or other treatment methods might be necessary to prevent skin contact with urine.