Gastroesophageal reflux disease (GERD) may not be closely related to staying up late. However, patients with GERD should still pay attention to rest, balance work and leisure, and try to minimize staying up late. The occurrence of GERD is considerably related to one's diet. If a patient consumes strong tea, coffee, spirits, spicy or irritating foods, or high-fat foods, it could easily trigger an episode of GERD or worsen the symptoms in patients. The primary symptoms of GERD include heartburn, belching, nausea, etc. Treatment involves suppressing stomach acid secretion and promoting gastrointestinal motility.