Does early-stage cirrhosis exhibit spleen enlargement?

Written by Wu Hai Wu
Gastroenterology
Updated on May 14, 2025
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In the early stages of cirrhosis, spleen enlargement may occur, but generally, it is only a mild enlargement of the spleen. If the spleen shows significant enlargement, it generally indicates that the cirrhosis is no longer in the early stages. The main symptoms in the early stages of cirrhosis include an enlarged spleen, as well as denser liver parenchyma echoes and an uneven liver capsule surface. Once these early signs of cirrhosis appear, it is necessary to identify the cause as soon as possible and adopt cause-specific treatment. For example, if the cirrhosis is due to alcohol abuse, then it is necessary to abstain from alcohol. If it is due to chronic hepatitis B virus infection, antiviral treatments such as entecavir should be used. (Please use medication under the guidance of a doctor.)

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Can cirrhosis caused by hepatitis B virus be cured?

Hepatitis B virus-induced cirrhosis was previously considered incurable, though its progression could be slowed. However, recent observations and studies have shown that a small fraction of patients with early-stage hepatitis B virus-induced cirrhosis can be cured. However, the proportion of these patients is extremely low. To draw an analogy, cirrhosis is like our houses. If the cement, steel bars, and brick structure are damaged, then the house is difficult to repair. Cirrhosis is akin to the structural damage of the house, making it hard to recover.

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How long does it take to see the effects of Chinese medicine in the early stages of cirrhosis?

As for how long it takes to see the effects of traditional Chinese medicine in the early stages of cirrhosis, it depends on the specific cause of the disease. Depending on different causes, the time to see effects may vary. For instance, if it is early-stage alcoholic cirrhosis or drug-induced early-stage cirrhosis, after abstaining from alcohol and stopping the use of some liver-damaging medications, then supplementing with traditional Chinese medicine treatment, effects can be seen quite quickly. If it is caused by viral hepatitis and has not undergone standard antiviral treatment, relying solely on oral intake of traditional Chinese medicine, it might take a relatively long time to see some effects. Furthermore, the effects will be better after undergoing antiviral treatment.

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Written by Si Li Li
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Can the liver regrow after partial removal due to cirrhosis?

First, let us understand the causes of cirrhosis. The most common cause is chronic hepatitis B, which can develop into hepatitis B-related cirrhosis over time. The second is chronic hepatitis C, which can also lead to hepatitis C and cirrhosis in the long term. Another type is alcoholic cirrhosis, which occurs due to long-term excessive alcohol consumption. Cirrhosis involves the hardening of the entire liver, not just parts of it; the whole organ becomes hardened, not just certain sections. Once the entire liver is hardened due to cirrhosis, it is not possible to just remove a part and expect a normal liver to grow back. Thus, unlike what might be suggested in some discussions, it is not feasible to remove a part of a cirrhotic liver with the expectation of regeneration. Liver cirrhosis cannot be partially removed; it is not operable in this way.

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Infectious Diseases
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How long can one live with hepatitis B-related cirrhosis?

We cannot give a definite answer on how long a patient with hepatitis B-related cirrhosis can live, as the life expectancy in late-stage cirrhosis is influenced by many factors including treatment measures, lifestyle adjustments, daily healthcare, and physical condition. Patients in the compensated stage of cirrhosis, if treated and the progression of cirrhosis is halted, with normal liver function and negative hepatitis B virus replication indicators, can work normally. In this state, the quality of life is good, and they can live to 70 to 80 years old. For patients in the decompensated stage of cirrhosis, if untreated and the cirrhosis is allowed to progress, about 70 to 80% may die within 5 years; however, aggressive treatment, including traditional Chinese medicine for liver fibrosis and cirrhosis, combined with antiviral treatment, bleeding prevention, liver protection, and liver transplantation, can significantly increase the survival time of patients.

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Can alcoholic cirrhosis be contagious?

Cirrhosis caused by hepatitis formed by alcohol is not contagious in clinical settings. Contagious cirrhosis generally refers to viral hepatitis, such as hepatitis A, B, C, and E, which are infectious. Alcoholic cirrhosis, primarily caused by drinking, is not caused by viruses; hence, alcohol does not facilitate transmission between people. The common transmission modes involve fecal-oral routes, for instance, through blood and bodily fluids in hepatitis A and B. In contrast, alcoholic liver disease is relatively safe, so there is no need to worry about it being contagious.