Does early-stage cirrhosis cause itchy skin?

Written by Wu Hai Wu
Gastroenterology
Updated on May 16, 2025
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Generally, early-stage cirrhosis does not cause itchy skin. However, if a patient with cirrhosis has a high jaundice index, or the cirrhosis is caused by bile stasis or primary sclerosing cholangitis, itchy skin might occur. Once a patient with cirrhosis experiences itchy skin, it is recommended to complete relevant auxiliary examinations, such as liver function tests, routine blood tests, gastroscopy, and abdominal ultrasound, to determine the extent of the cirrhosis and actively identify the causes of the cirrhosis and itchy skin, to promptly treat the condition based on the underlying causes.

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Written by Si Li Li
Gastroenterology
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Does early-stage cirrhosis hurt when pressed?

The anatomical location of the liver is covered by the ribs, so generally, the liver cannot be felt below the lower edge of the ribs, and since it is covered by the ribs, the liver cannot be pressed, hence there is no such thing as pain upon pressing. When we generally check for liver pain, we use percussion pain. By percussing the area of the liver, which is under the rib area, pain can be elicited in the liver, this is called percussion pain. The liver generally does not have tenderness because it simply cannot be pressed. Early stages of liver cirrhosis usually exhibit little to no pain sensation. However, some symptoms might appear during the decompensated phase, such as fatigue, weight loss, dull complexion, reduced urine output, edema, and spider angiomata, among other symptoms.

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Written by Wu Hai Wu
Gastroenterology
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Do you need a liver transplant in the early stages of cirrhosis?

In the early stages of cirrhosis, liver transplant is not necessary. Early-stage cirrhosis requires timely and comprehensive auxiliary examinations to determine the cause of the cirrhosis. This includes determining whether it is due to viral hepatitis, cholestatic hepatitis, or drug-induced hepatitis, among others. Once a patient exhibits early signs of cirrhosis, it is crucial to treat the specific cause and symptoms actively, and undertake proactive liver protection treatments. It is also essential to prevent complications associated with cirrhosis, such as esophageal and gastric variceal bleeding, primary liver cancer, hepatorenal syndrome, liver disease, and ascites.

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Written by Wu Hai Wu
Gastroenterology
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What causes stomach pain in the early stages of cirrhosis?

Early stages of cirrhosis may present with stomach pain, likely due to erosion in the stomach caused by the cirrhosis. It is recommended to promptly complete a gastroscopy to rule out the presence of portal hypertensive gastropathy or esophagogastric varices, while also testing for Helicobacter pylori infection. If the diagnosis is confirmed, treatment should be based on the underlying cause. Consider using proton pump inhibitors to suppress stomach acid secretion, or using antacids like aluminum magnesium carbonate to protect the stomach lining. (Please use medication under the guidance of a doctor.)

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Written by Wu Hai Wu
Gastroenterology
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Will the platelet count be low in the early stages of cirrhosis?

The early stage of cirrhosis does not cause a decrease in platelets. Patients in the early stages of cirrhosis often have no obvious symptoms and may only exhibit fatigue, weight loss, jaundice, etc. However, once a patient with cirrhosis develops splenic hyperfunction, it can easily lead to a decrease in platelets, where the platelet count may drop to 100,000 per microliter. In such cases, it might be necessary to perform procedures like splenic embolization or splenectomy for antimicrobial treatment, and it is also important to prevent other complications of cirrhosis, such as esophageal and gastric varices, etc.

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Written by Wu Hai Wu
Gastroenterology
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Is the pain obvious in the early stages of cirrhosis?

In the early stages of cirrhosis, the pain is not very obvious. Patients in the early stages of cirrhosis may experience vague discomfort in the upper right abdomen, while others may never experience pain at all. Those in the early stages may also have symptoms such as belching, fatigue, acid reflux, jaundice, and dark urine. Further comprehensive auxiliary examinations are needed, such as liver function tests and abdominal imaging studies. At the same time, it is important to identify the cause of early-stage cirrhosis in patients as soon as possible and adopt appropriate treatment measures based on different causes. For instance, if it is caused by alcohol, then treatment should involve abstaining from alcohol.