Is hepatitis B with liver cirrhosis severe?

Written by Yuan Lin Yan
Infectious Disease
Updated on September 23, 2024
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Hepatitis B-related cirrhosis is a form of liver cirrhosis caused by the hepatitis B virus, and it is more severe than chronic hepatitis B. However, cirrhosis can be categorized into compensated cirrhosis and decompensated cirrhosis. Decompensated cirrhosis refers to the advanced stages of cirrhosis, characterized by significant hardening of the liver, and complications such as ascites, hepatic encephalopathy, and gastrointestinal bleeding may occur. This type of cirrhosis is severe and has a high mortality rate, and even timely antiviral therapy against hepatitis B cannot effectively delay the progression of the disease. Compensated cirrhosis refers to the early stages of cirrhosis, where complications like ascites, hepatic encephalopathy, and gastrointestinal bleeding are not present, making this type of cirrhosis comparatively less severe. With timely antiviral therapy against hepatitis B, the progression of cirrhosis can be delayed.

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Written by Zhang Jian Kang
Infectious Disease
1min 8sec home-news-image

Is hepatitis B cirrhosis contagious?

If hepatitis B is not well controlled, it can easily lead to the occurrence of cirrhosis. After the hepatitis B virus infects the human body, it causes repeated inflammatory damage to the liver, with recurring abnormalities in liver function. If during this period there is no formal antiviral treatment or lack of attention, it is very likely to lead to the development of cirrhosis. Once cirrhosis from hepatitis B occurs, it is generally irreversible. Cirrhosis due to hepatitis B is also an infectious disease, and its level of infectiousness mainly depends on the presence of the virus. If the viral load is positive, indicated by a positive HBV-DNA test, then it is infectious. If HBV-DNA is negative, then it is not infectious. Therefore, whether cirrhosis from hepatitis B is infectious primarily depends on the level of HBV-DNA.

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Written by Wu Hai Wu
Gastroenterology
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Do you need a liver transplant in the early stages of cirrhosis?

In the early stages of cirrhosis, liver transplant is not necessary. Early-stage cirrhosis requires timely and comprehensive auxiliary examinations to determine the cause of the cirrhosis. This includes determining whether it is due to viral hepatitis, cholestatic hepatitis, or drug-induced hepatitis, among others. Once a patient exhibits early signs of cirrhosis, it is crucial to treat the specific cause and symptoms actively, and undertake proactive liver protection treatments. It is also essential to prevent complications associated with cirrhosis, such as esophageal and gastric variceal bleeding, primary liver cancer, hepatorenal syndrome, liver disease, and ascites.

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Written by Wang Ji Zhong
Internal Medicine
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Symptoms of alcoholic liver cirrhosis

Long-term alcohol consumption can lead to alcoholic liver disease, with alcoholic liver cirrhosis being one of its main manifestations. Initially, it presents with reduced liver function, symptoms such as loss of appetite, abdominal pain, bloating, vomiting, aversion to oily foods, diarrhea, and nausea, which are indicative of hepatitis. Additionally, there may be darkening of the skin, menstrual irregularities, and even signs like liver palms and spider angiomas due to metabolic disorders. Furthermore, disruptions in carbohydrate metabolism can lead to nutritional excess, increasing lipid levels in the body and leading to fatty liver and hyperlipidemia. There can also be abnormal protein synthesis, resulting in ascites, pleural effusion, and other symptoms of liver dysfunction. Additionally, abnormalities in vitamin metabolism can cause rough skin and edema. Coagulation factors are often abnormal as well, leading to symptoms such as bleeding gums and nosebleeds. Therefore, it is crucial to seek medical attention promptly in these situations to restore normal health.

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Written by Yang Chun Guang
Gastroenterology
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Can alcoholic cirrhosis be contagious?

Cirrhosis caused by hepatitis formed by alcohol is not contagious in clinical settings. Contagious cirrhosis generally refers to viral hepatitis, such as hepatitis A, B, C, and E, which are infectious. Alcoholic cirrhosis, primarily caused by drinking, is not caused by viruses; hence, alcohol does not facilitate transmission between people. The common transmission modes involve fecal-oral routes, for instance, through blood and bodily fluids in hepatitis A and B. In contrast, alcoholic liver disease is relatively safe, so there is no need to worry about it being contagious.

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Written by Wu Hai Wu
Gastroenterology
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Will cirrhosis continue to progress if there are no symptoms?

Cirrhosis may not have symptoms, yet it can still progress. There are various causes of cirrhosis, such as viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, drug-induced hepatitis, and fatty liver disease, among others. If the underlying causes are not removed, cirrhosis can continue to progress even without symptoms. For example, in chronic hepatitis B, if no effective antiviral treatment is administered, the patient may progress to decompensated cirrhosis in the absence of symptoms, which in severe cases, can lead to the development of liver cancer. Therefore, once cirrhosis is diagnosed, it is crucial to actively identify the cause and adopt different treatments according to the specific cause, such as abstaining from alcohol if the cirrhosis is alcohol-related.