The adenoids are normal anatomical structures located in the nasopharynx. In childhood, the glandular tissue of the adenoids becomes enlarged, blocking the normal passages of the nasopharynx and leading to secondary diseases. Clinically, there are no drugs specifically targeting enlarged adenoids. However, other medications, such as mometasone nasal spray and montelukast sodium, may have some effect on adenoid enlargement and can help a minority of patients avoid surgery. Nonetheless, it is advised not to rely on these drugs as the primary treatment method for enlarged adenoids; the main treatment is surgical.