When does neonatal jaundice go away?

Written by Li Jiao Yan
Neonatology
Updated on March 04, 2025
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Neonatal jaundice is a common phenomenon in the newborn period, with 80% of full-term infants visibly exhibiting jaundice. Jaundice is divided into physiological jaundice and pathological jaundice. In full-term infants, physiological jaundice generally lasts about two weeks and ordinarily subsides within that time. For preterm infants, it typically does not last more than four weeks. However, if the jaundice progresses quickly, appears early, and is severe, reaching pathological levels, intervention and treatment are necessary. The duration of jaundice can vary depending on the baby’s condition. Without intervention, the duration of jaundice may be prolonged. Therefore, it is advisable to regularly monitor jaundice and actively intervene with treatment if abnormalities are present.

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Written by Li Jiao Yan
Neonatology
1min 37sec home-news-image

normal values of neonatal jaundice

Neonatal jaundice is the most common phenomenon in the neonatal period, generally divided into physiological jaundice and pathological jaundice. If the baby's values are within the normal range, it may be physiological jaundice, which does not require special intervention and will resolve on its own. Typically, normal physiological jaundice appears 2-3 days after birth, peaks around 4-5 days, begins to lessen about a week later, and resolves within two weeks, generally occurring in full-term infants born after 37 weeks. It's advisable for babies to have their jaundice monitored daily within the first two weeks, especially during the peak period, from 2-3 days to about a week or around ten days, when jaundice monitoring should be more frequent. Normally, it's best if the bilirubin levels in newborns do not exceed 6 mg/dL in the first 24 hours, 9 mg/dL within 24-48 hours, 12 mg/dL within 48-72 hours, and 15 mg/dL after 72 hours. These values are generally considered acceptable. Additionally, jaundice progression should not be too rapid; if bilirubin levels rise more than 5 mg/dL within 24 hours, it indicates too rapid an increase in jaundice. In such cases, it is also necessary to go to the hospital, where a neonatal doctor should assess the baby and decide if special treatment intervention is needed.

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Written by Li Jiao Yan
Neonatology
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Is it useful for newborns with jaundice to take probiotics?

Probiotics are useful for newborn jaundice. After oral administration of probiotics, they help establish a normal gut microbiota in babies and then reduce the enterohepatic circulation of bilirubin, which aids in the treatment of jaundice. Common probiotics, often referred to in layman's terms as live bacteria, include species like Saccharomyces boulardii, Bifidobacterium, or Lactobacillus, among others. These probiotics are available in pharmacies. Generally, for newborns, especially those who are breastfed and do not recover well from jaundice, oral probiotics can have a therapeutic effect on reducing jaundice, so it is suitable for newborn babies to consume certain probiotics.

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Written by Li Jiao Yan
Neonatology
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How long is the incubation period for neonatal jaundice?

Neonatal jaundice is the most common phenomenon in the neonatal period, especially in early neonates, which refers to newborns within the first week of life. About 80% of full-term infants can visually exhibit signs of jaundice. Jaundice can be categorized into physiological jaundice and pathological jaundice. Typically, physiological jaundice appears about two to three days after birth. If it is pathological jaundice, it may appear earlier, possibly within the first twenty-four hours after birth. Generally, if the jaundice appears early, progresses quickly, and is severe, it is necessary to intervene and treat promptly.

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Written by Yao Li Qin
Pediatrics
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What causes jaundice in newborns?

Neonatal jaundice is primarily due to the overproduction of bilirubin, which means a higher number of red blood cells are being destroyed, leading to an increased concentration of bilirubin in the blood. Additionally, there is a metabolic disorder of bilirubin in the child. The liver cells' ability to take up and bind bilirubin decreases, which can cause an increase in the concentration of unbound bilirubin in the serum, resulting in jaundice. This mainly occurs in cases of hypoxia, infection, and some congenital diseases, among others. Certain medications and reduced thyroid function can also present this symptom. The third issue is an impairment in the bile's ability to excrete bilirubin, which can occur when the child has neonatal hepatitis or congenital metabolic defects, leading to jaundice.

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Written by Shi Ji Peng
Pediatrics
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What are the symptoms of neonatal jaundice?

Neonatal jaundice generally appears on the 2nd to 3rd day after birth and can manifest with yellowing of the skin, conjunctiva, and oral mucosa. The degree of jaundice varies, usually more noticeable on the face and chest, but not present on the palms of the hands or soles of the feet. It is most apparent on the 4th to 6th day after birth. The duration of jaundice also varies; in full-term infants, jaundice typically subsides within 10-14 days after birth, whereas in premature infants, it can last until the third or even the fourth week. During this period, infants with physiological jaundice are generally in good condition without any other discomfort and do not require treatment. However, pathological jaundice must be investigated for its cause. Pathological jaundice is primarily characterized by an early onset, severe degree, prolonged duration, or recurrence of jaundice. In such cases, it is classified as pathological jaundice, and it is crucial to actively search for the cause and treat accordingly based on the identified cause.