Newborn jaundice can be divided into several types.

Written by Li Jiao Yan
Neonatology
Updated on January 01, 2025
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Neonatal jaundice is one of the common symptoms during the neonatal period, especially in early newborns. It can be a symptom of the normal developmental process of newborns, or it can be a manifestation of certain diseases. Neonatal jaundice is relatively common in newborns, with about 80% of full-term infants visibly showing jaundice. Jaundice is classified into physiological jaundice and pathological jaundice. If it is pathological jaundice, there are different classifications. Based on different characteristics of bilirubin elevation, it is divided into high direct bilirubinemia and high indirect bilirubinemia. Physiological jaundice does not require intervention. However, if it is pathological jaundice, it is necessary to clarify its classification and determine which type it belongs to. Generally, if it is pathological jaundice, timely intervention and treatment are needed. If untreated, and if the jaundice level significantly increases, it may lead to serious complications.

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Written by Li Jiao Yan
Neonatology
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How to treat neonatal jaundice

Neonatal jaundice is the most common phenomenon during the neonatal period and generally falls into two categories: physiological jaundice and pathological jaundice. As the name suggests, physiological jaundice is a normal physiological phenomenon. It typically appears in full-term babies on days 2-3, peaks on days 4-5, and gradually decreases around day 7, and completely subsides within two weeks. This type does not require intervention as the baby is generally in good condition and usually does not need treatment. Jaundice that appears early, progresses quickly, is severe, or lasts a long time is considered pathological jaundice. The diagnosis of pathological jaundice is generally made by a doctor. It is recommended that babies be monitored daily for jaundice within the first two weeks after birth. Based on the bilirubin levels, if it is high, it is advisable to seek a thorough examination from a neonatologist. Pathological jaundice requires timely intervention, especially considering liver function. If there is a significant increase in indirect bilirubin, this type of jaundice can be neurotoxic. Persistent high jaundice might affect the brain, so prompt intervention is necessary. Hospitalization for jaundice treatment will depend on the cause, and treatment will be symptomatic. The cause might be other pathological factors; removing the cause while treating the jaundice is the usual approach. Common treatment for high indirect bilirubin involves phototherapy. If conjugated bilirubin is elevated, the underlying cause might be more complex and treatment more challenging. Therefore, if jaundice is detected and there is uncertainty, it is advised to promptly visit a hospital for intervention by a neonatal specialist and necessary treatment.

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Written by Li Jiao Yan
Neonatology
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normal values of neonatal jaundice

Neonatal jaundice is the most common phenomenon in the neonatal period, generally divided into physiological jaundice and pathological jaundice. If the baby's values are within the normal range, it may be physiological jaundice, which does not require special intervention and will resolve on its own. Typically, normal physiological jaundice appears 2-3 days after birth, peaks around 4-5 days, begins to lessen about a week later, and resolves within two weeks, generally occurring in full-term infants born after 37 weeks. It's advisable for babies to have their jaundice monitored daily within the first two weeks, especially during the peak period, from 2-3 days to about a week or around ten days, when jaundice monitoring should be more frequent. Normally, it's best if the bilirubin levels in newborns do not exceed 6 mg/dL in the first 24 hours, 9 mg/dL within 24-48 hours, 12 mg/dL within 48-72 hours, and 15 mg/dL after 72 hours. These values are generally considered acceptable. Additionally, jaundice progression should not be too rapid; if bilirubin levels rise more than 5 mg/dL within 24 hours, it indicates too rapid an increase in jaundice. In such cases, it is also necessary to go to the hospital, where a neonatal doctor should assess the baby and decide if special treatment intervention is needed.

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Written by Li Jiao Yan
Neonatology
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Symptoms of higher neonatal jaundice

Neonatal jaundice is one of the common symptoms during the neonatal period, with about 80% of full-term infants visibly exhibiting jaundice. Jaundice may occur as part of the normal developmental process or as a manifestation of certain diseases. It is categorized into physiological jaundice and pathological jaundice. High levels of jaundice may indicate pathological jaundice. Generally, if the baby's skin and mucous membranes are obviously yellow, and the jaundice has spread to the limbs or even beyond the palms and soles, which are also notably yellow, it is a sign that the jaundice is severe. Parents can typically observe a clear yellowing of the sclera, the white part of the eyes. The baby may also show other signs of discomfort, such as significant crying and restlessness, pronounced vomiting or increased regurgitation, or even symptoms like abdominal bloating, diarrhea, reluctance to feed, prolonged feeding times, lethargy, or potentially even fever and other discomforts.

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Written by Li Jiao Yan
Neonatology
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Neonatal jaundice symptoms

Neonatal jaundice is most commonly seen in the skin and mucous membranes, and the sclera, or what we refer to as the eyes, presenting with a yellow discoloration of the white part. The most common symptom is yellowing of the skin. There may also be other symptoms such as crying and restlessness, fever, or rapid and irregular breathing. Some babies might sleep longer than usual, have difficulty feeding, or experience issues with bowel movements, such as a significant decrease in stool frequency or a reduction in urine output. These could be accompanying symptoms of neonatal jaundice. Each baby presents differently with jaundice; more accompanying symptoms often indicate a more severe condition. If the jaundice is limited to skin discoloration without other significant symptoms, it may indicate an early stage of the condition. Generally, if the jaundice is pronounced, it is considered pathological jaundice, and it is advisable to go to the hospital. A pediatric specialist can conduct relevant examinations and decide if immediate intervention and treatment are necessary.

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Written by Li Jiao Yan
Neonatology
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Neonatal jaundice peak period is a few days.

Neonatal jaundice is one of the common symptoms during the neonatal period; it could be a normal physiological phenomenon, or it might be an external manifestation of certain diseases. Typically, physiological jaundice appears two to three days after birth, reaches its peak within four to five days in full-term infants, and may appear sooner and be more severe in preterm infants due to their less mature liver function. The peak period lasts longer for preterm babies; generally, in full-term infants, jaundice usually starts declining about a week later, subsiding around ten days, generally not lasting more than two weeks.