What should I do if I have advanced breast cancer with breast necrosis?

Written by Lin Yang
Breast Surgery
Updated on April 29, 2025
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Firstly, radiotherapy can be used, localized radiation therapy, which will achieve certain local control effects. It can also provide surgical opportunities for some breast cancer patients who are otherwise inoperable. Additionally, it can relieve pain, reduce compression symptoms, and stop bleeding in ulcerated cancer lesions, thereby improving the patient's quality of life. If chemotherapy is possible, it should be pursued as it can reduce distant and extensive metastases. Then, if surgery is feasible, the ulcerated or already healed surgical incisions can be excised and sutured to improve the patient's quality of life.

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Written by Zhang Chao Jie
Breast Surgery
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Breast cancer symptoms

The symptoms of breast cancer depend on the severity of the cancer and whether there are any signs of metastasis or recurrence. It is important to emphasize that over 90% of breast cancer cases do not involve pain as a symptom. This means that the earliest symptoms of breast cancer are usually determined by whether the cancer is in its early or late stages. Early-stage breast cancer may have no symptoms at all, or there may be signs such as a lump or hard nodule in the breast, discharge from the nipple, especially coffee-colored or bloody discharge. Late-stage symptoms can include changes in the skin of the breast resembling the texture of an orange peel, palpable large lymph nodes in the armpit that are hard but neither painful nor itchy. If the cancer has metastasized to the lungs, chest cavity, pleura, liver, bones, or head, symptoms might include chest pain, coughing, difficulty breathing, abdominal distention, bone pain or fractures, as well as headaches, eye pressure, and dizziness, among others. Therefore, the symptoms of breast disease depend on whether the cancer is in its early stages; if it is in a late stage and has metastasized to other parts, corresponding symptoms will be present. It is also important to remember that early-stage breast cancer may not show any symptoms at all.

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Written by Fan Hong Qiao
Breast Health Department
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What is invasive breast cancer?

Invasive breast cancer is the most common tumor in women, accounting for 22% of all malignant tumors in females. Invasive breast cancer refers to a malignant tumor where cancer cells have broken through the basement membrane of the breast ducts or lobular alveoli and invaded the interstitium. The vast majority of invasive breast cancers are adenocarcinomas, originating from the epithelial cells of the breast parenchyma, especially from the terminal duct lobular units. Its characteristics include the tumor's infiltration into adjacent tissues and a marked tendency for distant metastasis.

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Written by Lin Yang
Breast Surgery
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Early symptoms of breast cancer

The initial symptom of early breast cancer is a painless, single small lump with no redness or swelling around the skin. However, a few individuals may experience nipple discharge, typically fresh or stale blood. There may be slight indentations on the skin and some itching. Visually, some individuals might notice inverted nipples and lymph node metastasis under the armpits. The lump often has unclear boundaries, is hard in texture, has limited mobility, adheres to the skin, and is difficult to move within the breast tissue.

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Written by Gong Chun
Oncology
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Early-stage breast cancer symptoms

Early-stage breast cancer may exhibit several symptoms. The first is the presence of breast lumps. The second symptom might be nipple discharge, which can be serous, watery, or milky in nature. The third symptom might involve changes in the skin over the breast tumor, including skin adhesion, such as dimpling, engorgement of superficial veins, skin reddening, localized increase in temperature, and an orange-peel texture. The fourth symptom includes abnormalities of the nipple and areola, potentially featuring nipple retraction, erosion of the nipple, thickening of the nipple epithelium, and reddening. The fifth symptom could be breast pain.

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Written by Zhang Chao Jie
Breast Surgery
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What is breast cancer OFS?

Breast cancer OFS is a method in the field of breast cancer treatment, where OFS stands for ovarian function suppression. Thus, OFS refers to the suppression of ovarian function, preventing the ovaries from releasing sex hormones, thereby achieving the purpose of treating breast cancer. There are three methods of OFS. The first method is direct surgical removal, medically also called castration. Here, "castration" implies the removal of ovarian influence, and this surgical method is actually one of the most effective methods of OFS. The second method is chemical castration. The most commonly used drug for this is called Gosserelin, which is used for drug-induced ovarian function suppression. The third method of ovarian function suppression is radiotherapy. However, because it is difficult to achieve the desired results and it can cause serious complications, this method is basically no longer used. OFS is necessary for breast cancer patients who are positive for estrogen receptor ER and progesterone receptor PR, and it is used only under these conditions.