Appendicitis primarily occurs as inflammation in the lower right abdomen due to its association with the location of the appendix, which is most often situated in the right iliac fossa. In very rare cases, patients with malrotation of the intestine or situs inversus may have the appendix located on the left side, or it may be elevated due to specific conditions during pregnancy. Generally, the appendix is an intra-peritoneal organ and its position can be variable. However, because the base of the appendix has a relatively constant relationship with the cecum, there are typically six clinical manifestations of the appendix's position: pre-ileal, pelvic, retrocecal, subcecal, post-ileal, and lateral cecal positions. For cases of appendicitis with clear diagnosis, surgical treatment is predominantly considered.