The pain of acute appendicitis is mainly abdominal pain. Currently, there are no available data for reference to understand the level of pain in appendicitis, and the pain associated with acute appendicitis is related to the individual's constitution and the extent of inflammation in the appendix. If the inflammation is mild, limited only to the serosal layer, then the pain is relatively mild and tolerable. If the inflammation is more extensive or involves pus formation, perforation, and affects the peritoneum, it leads to noticeable peritonitis and causes severe, knife-like pain, making the patient scared to move and covered in profuse sweat; the pain is quite severe. For acute appendicitis, surgery is currently advocated as the treatment method.