Chronic non-atrophic gastritis

Written by Si Li Li
Gastroenterology
Updated on January 23, 2025
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Chronic non-atrophic gastritis is also known as chronic superficial gastritis. It is a classification of chronic gastritis, which also includes chronic atrophic gastritis and special types of gastritis as other classifications. Chronic non-atrophic gastritis refers to a condition where the glands in the gastric mucosa do not show atrophy, thus it is called chronic non-atrophic gastritis. Generally, the endoscopic appearance of the gastric mucosa being hyperemic, edematous, or eroded can lead to a diagnosis of chronic non-atrophic gastritis. Treatment mainly focuses on acid suppression, protecting the stomach, promoting gastric motility, and protecting the gastric mucosa. If there is a positive Helicobacter pylori infection, eradication treatment for Helicobacter pylori is required. Patients with chronic non-atrophic gastritis should primarily consume a light and easy-to-digest diet.

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"Mild active phase of atrophic gastritis"

Mild active phase of atrophic gastritis refers to the period when gastritis is occurring, typically caused by improper diet. This might be due to overeating or consuming greasy, spicy, and irritating foods, leading to exacerbation of the condition. Clinical manifestations include stomach pain, nausea, vomiting, and decreased appetite, which are inevitably linked to daily life habits. Furthermore, mental stress, excessive pressure, staying up late, and overfatigue can also have an impact.

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Is atrophic gastritis of the gastric antrum serious?

Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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Written by Wu Hai Wu
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Does chronic atrophic gastritis require lifelong medication?

If the patient has lifelong atrophic gastritis, they may need to follow a doctor's advice and take medications that increase mucosal nutrition for life, such as sucralfate, live gastric ketone, prostaglandin E1, etc. The main causes of atrophic gastritis are Helicobacter pylori infection, as well as other factors such as autoimmune mechanisms, genetic factors, and decreased gastric mucosal barrier function. The main symptoms of atrophic gastritis include obscure pain in the upper abdomen, distension, burning pain, along with accompanying symptoms like weight loss and anemia. Treatment for atrophic gastritis involves eradicating Helicobacter pylori and using medications that protect the gastric mucosa.

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Written by Xie Zheng Yuan
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How long does it take to treat atrophic gastritis with erosion?

Atrophic gastritis with erosion is a type of chronic gastritis and has a lengthy course of disease. Through treatment, the erosions may heal within six to eight weeks. However, reversing the atrophy of the gastric mucosa is a long-term and slow process, and there are no specific effective drugs clinically available. Some traditional Chinese medicines and proprietary Chinese medicines may be effective, but it typically takes at least six months. Therefore, the duration required to treat atrophic gastritis with erosion varies from person to person, depending on individual differences.

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Written by Si Li Li
Gastroenterology
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Is atrophic gastritis easy to treat?

Atrophic gastritis is a type of chronic gastritis characterized by the atrophy of gastric mucosal glands. It carries a certain risk of becoming cancerous. The main symptoms include upper abdominal pain, postprandial fullness, heartburn, indigestion, belching, and acid reflux. Gastroscope examination reveals atrophy of the gastric glands, and a biopsy is needed for a pathological examination to confirm the diagnosis of chronic atrophic gastritis. In terms of treatment, the first step is to eradicate Helicobacter pylori, which includes a regimen of one proton pump inhibitor, two antibiotics, and one bismuth agent, lasting for 14 days. This is followed by acid suppression and mucosal repair treatments. Additionally, the treatment with traditional Chinese medicine plays a significant role in managing atrophic gastritis. This condition is challenging to treat, has poor outcomes, is prone to relapse, and carries a risk of cancer transformation.