Conservative medication treatment for external hemorrhoidal nodules can only reduce their size, but cannot completely eliminate them.

For instance, if an external hemorrhoidal nodule develops inflammatory edema, one can take oral Diltiazem tablets, combined with anal wash or potassium permanganate solution for local sitz baths, and apply Golden Ointment externally, which can achieve good anti-swelling effects.

However, if the external hemorrhoidal nodule is significantly enlarged, or even forms a thrombus causing pain and swelling in the anus, simply using medication cannot effectively improve the symptoms.

In such cases, surgical intervention is required to eliminate the nodule, such as external hemorrhoidectomy. Post-surgery, dressing changes such as Mupirocin ointment, red oil gauze strips, Golden Ointment, and other medications are recommended. Furthermore, the patient should maintain good bowel habits, avoiding prolonged toilet time or excessive straining.