Can Helicobacter pylori infection recur after treatment?

Written by Si Li Li
Gastroenterology
Updated on March 21, 2025
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Helicobacter pylori, once treated, does not recur, but it is possible to be infected again after the treatment is completed.

Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%, so it is important to be cautious during communal meals. Due to the Chinese dietary habit of sharing dishes using the same chopsticks, it is easy to spread Helicobacter pylori. Therefore, it is advisable to use serving chopsticks, which can significantly reduce the infection rate of Helicobacter pylori.

If reinfected with Helicobacter pylori, it is necessary to undergo eradication treatment again. The treatment involves a proton pump inhibitor, two types of antibiotics, and a bismuth agent, totaling a 14-day treatment. After infection with Helicobacter pylori, dietary precautions are also needed, focusing on a light, easily digestible diet, and avoiding difficult-to-digest foods.

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Written by Wu Hai Wu
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Can I drink coffee during the treatment for Helicobacter pylori?

It is not recommended to drink coffee during the treatment for Helicobacter pylori. During the treatment for Helicobacter pylori infection, it is advised to consume more fresh vegetables and fruits rich in vitamins, maintain regular meals, and eat light, easily digestible foods. Avoid strong alcohol, strong tea, coffee, and also greasy foods. The main methods for detecting Helicobacter pylori infection are the carbon-13 urea breath test or the carbon-14 urea breath test. If the test results are positive, a standard eradication treatment using a bismuth-containing quadruple therapy for two weeks should be implemented. Additionally, a re-examination is needed one month after discontinuing the medication to confirm whether the eradication is complete.

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Written by Wang Jing Bin
Gastroenterology
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How to treat Helicobacter pylori positivity?

A positive test for Helicobacter pylori requires distinguishing the specific method used for detection. If it is a positive result from a Helicobacter pylori antibody test, a breath test, including both the Carbon-14 and Carbon-13 breath tests, should be conducted. If the breath test comes back positive, further examinations are necessary, including gastroscopy and analysis of Helicobacter pylori virulence factors. The analysis of virulence factors can help determine if the Helicobacter pylori infection is highly toxic. If positive, it may indicate a potential for severe gastric diseases and necessitate treatment. For individuals with a positive Helicobacter pylori breath test, a gastroscopy is also recommended, as it is the only way to precisely determine the type of gastric disease present, such as ulcers or gastritis. Depending on the gastroscopy results, some individuals may need eradication treatment for Helicobacter pylori, especially those with a history of gastric ulcers, a family history of gastric cancer, gastric polyps, erosive gastritis, or gastric mucosa-associated lymphoid tissue lymphoma. Others, if the virulence factor analysis is negative, might not require immediate treatment for Helicobacter pylori. However, if a patient insists on treatment for Helicobacter pylori, it can be considered, but it must be clear that there are risks involved and that the treatment should be conducted properly. Finally, treatment for Helicobacter pylori is not recommended for minors, i.e., individuals under 18 years of age.

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Written by Jiang Guo Ming
Gastroenterology
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Helicobacter pylori symptoms

Helicobacter pylori itself is just a bacterium, often parasitizing the stomach or oral cavity of the human body. It cannot be said that Helicobacter pylori has symptoms, but rather that symptoms may occur after being infected by Helicobacter pylori. Many normal people infected with Helicobacter pylori may not exhibit any discomfort. However, if Helicobacter pylori causes gastritis or peptic ulcers, etc., related symptoms may appear. For instance, abdominal pain, bloating, belching, acid reflux, and so on; in cases of peptic ulcers, corresponding symptoms, such as periodic, recurrent episodes of upper abdominal pain associated with eating and so forth, may also occur and will need to be determined based on the specific situation.

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Written by Wang Hui Jie
Gastroenterology
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Can Helicobacter pylori cure itself?

Can Helicobacter pylori be self-healing? Helicobacter pylori is very stubborn; once infected, adults who do not undergo formal therapeutic interventions will be afflicted for life, meaning the cure rate is close to zero. Children, whose immune functions are not yet fully developed, may experience multiple exposures on the gastric mucosa and short-term colonization before Helicobacter pylori settles permanently, which could potentially lead to either colonization or loss of the bacteria. White populations have stronger immune resistance than colored populations. Tracking reports indicate that 50% of white children may lose the infection after contracting it, while only 4% of black children might. Generally, the infection rate is higher than the self-healing rate, indicating that Helicobacter pylori infections in adults are generally not self-resolving.

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Written by Si Li Li
Gastroenterology
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Does the breath test for Helicobacter pylori require fasting?

Currently, the detection of Helicobacter pylori is highly accurate and specific, and a rapid, simple, and effective method is the Carbon-14 breath test. The Carbon-14 breath test requires no eating within six hours, so it is best to take it on an empty stomach. Therefore, it is preferable to test for Helicobacter pylori on an empty stomach. Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. Helicobacter pylori is the principal cause of chronic gastritis, peptic ulcers, or gastric cancer. Therefore, if symptoms of the digestive system occur, such as belching, acid reflux, upper abdominal pain, nausea, and poor appetite, it is advisable to conduct a test for Helicobacter pylori, specifically the Carbon-14 breath test, to confirm the infection of Helicobacter pylori.