Does the breath test for Helicobacter pylori require fasting?

Written by Si Li Li
Gastroenterology
Updated on November 15, 2024
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Currently, the detection of Helicobacter pylori is highly accurate and specific, and a rapid, simple, and effective method is the Carbon-14 breath test.

The Carbon-14 breath test requires no eating within six hours, so it is best to take it on an empty stomach. Therefore, it is preferable to test for Helicobacter pylori on an empty stomach. Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. Helicobacter pylori is the principal cause of chronic gastritis, peptic ulcers, or gastric cancer. Therefore, if symptoms of the digestive system occur, such as belching, acid reflux, upper abdominal pain, nausea, and poor appetite, it is advisable to conduct a test for Helicobacter pylori, specifically the Carbon-14 breath test, to confirm the infection of Helicobacter pylori.

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Written by Si Li Li
Gastroenterology
1min 3sec home-news-image

Is erosive gastritis related to Helicobacter pylori?

Helicobacter pylori infection has been confirmed as the primary cause of chronic gastritis, peptic ulcers, and gastric cancer. Erosive chronic gastritis is a type of chronic gastritis, thus there is a certain relationship between erosive gastritis and Helicobacter pylori, but not all chronic gastritis is caused by Helicobacter pylori; some are, but others are not. Therefore, if erosive gastritis occurs, it is necessary to conduct a carbon-14 breath test to determine whether there is an infection of Helicobacter pylori. If the Helicobacter pylori infection is positive, a 14-day anti-Helicobacter pylori treatment should be administered. The treatment includes a proton pump inhibitor, two antibiotics, and a bismuth agent. After treatment, most of the Helicobacter pylori will convert from positive to negative.

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Written by Yang Chun Guang
Gastroenterology
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Can a barium meal detect Helicobacter pylori?

The most commonly used test for detecting Helicobacter pylori at present is the breath test, which generally comes in two types: carbon-13 and carbon-14, though the testing method is basically fixed. A barium meal test can only detect whether there are large gastric ulcers or the presence of gastric cancer, but Helicobacter pylori is quite small and cannot be detected through a barium meal. Therefore, the detection of Helicobacter pylori typically relies on traditional methods, such as breath tests or tests performed during gastroscopy.

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Written by Wu Hai Wu
Gastroenterology
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Can I take vitamins B1 and B12 during treatment for Helicobacter pylori?

During the treatment of Helicobacter pylori, it is possible to consume Vitamin B1 and Vitamin B12. The treatment of Helicobacter pylori infection can consider using a bismuth-containing quadruple therapy for two weeks to eradicate the infection. During the treatment of Helicobacter pylori infection, one can also eat fresh vegetables and fruits rich in vitamins, such as kiwis, bananas, apples, etc. It is important to eat regularly and in moderation, consume light, easily digestible foods, and avoid overeating. Spicy and stimulative foods should be avoided, including strong alcohol, strong tea, coffee, etc. At the same time, patients with Helicobacter pylori infection should also ensure adequate rest.

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Written by Wang Jing Bin
Gastroenterology
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How to treat Helicobacter pylori positivity?

A positive test for Helicobacter pylori requires distinguishing the specific method used for detection. If it is a positive result from a Helicobacter pylori antibody test, a breath test, including both the Carbon-14 and Carbon-13 breath tests, should be conducted. If the breath test comes back positive, further examinations are necessary, including gastroscopy and analysis of Helicobacter pylori virulence factors. The analysis of virulence factors can help determine if the Helicobacter pylori infection is highly toxic. If positive, it may indicate a potential for severe gastric diseases and necessitate treatment. For individuals with a positive Helicobacter pylori breath test, a gastroscopy is also recommended, as it is the only way to precisely determine the type of gastric disease present, such as ulcers or gastritis. Depending on the gastroscopy results, some individuals may need eradication treatment for Helicobacter pylori, especially those with a history of gastric ulcers, a family history of gastric cancer, gastric polyps, erosive gastritis, or gastric mucosa-associated lymphoid tissue lymphoma. Others, if the virulence factor analysis is negative, might not require immediate treatment for Helicobacter pylori. However, if a patient insists on treatment for Helicobacter pylori, it can be considered, but it must be clear that there are risks involved and that the treatment should be conducted properly. Finally, treatment for Helicobacter pylori is not recommended for minors, i.e., individuals under 18 years of age.

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Written by Wu Hai Wu
Gastroenterology
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Why is there an increase in flatulence after the treatment of Helicobacter pylori?

After treatment for Helicobacter pylori, having more flatulence generally isn't directly related to the treatment, as the medication used includes proton pump inhibitors, antibiotics such as amoxicillin, clarithromycin, as well as bismuth citrate potassium. None of these drugs typically cause increased flatulence. If a patient experiences more flatulence after treatment, it might be due to functional dyspepsia. At this point, treating the condition with medications that regulate the gut flora, such as combined lactobacilli and Bifidobacterium triple live bacteria, might be effective. If the increased flatulence persists, it is advisable to promptly undergo a digital colonoscopy to rule out the possibility of organic intestinal diseases. (Specific medications should be used under the guidance of a doctor.)