How to treat Helicobacter pylori infection

Written by Si Li Li
Gastroenterology
Updated on December 09, 2024
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Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. The carbon-14 breath test can be used to detect the presence of Helicobacter pylori infection. If the infection is positive and is accompanied by some symptoms or diseases of the digestive system, eradication treatment for Helicobacter pylori is required.

The treatment regimen consists of a proton pump inhibitor, two antibiotics, and a bismuth agent, lasting for 14 days. After stopping the medication for a month, the carbon-14 breath test is rechecked to confirm whether the Helicobacter pylori has been converted to negative. If the conversion is negative, it indicates that the eradication treatment for Helicobacter pylori was successful. Helicobacter pylori has been confirmed as the main cause of chronic gastritis, peptic ulcer, and gastric cancer, thus if the Helicobacter pylori infection is positive, eradication treatment is necessary.

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Written by Si Li Li
Gastroenterology
1min 3sec home-news-image

Is erosive gastritis related to Helicobacter pylori?

Helicobacter pylori infection has been confirmed as the primary cause of chronic gastritis, peptic ulcers, and gastric cancer. Erosive chronic gastritis is a type of chronic gastritis, thus there is a certain relationship between erosive gastritis and Helicobacter pylori, but not all chronic gastritis is caused by Helicobacter pylori; some are, but others are not. Therefore, if erosive gastritis occurs, it is necessary to conduct a carbon-14 breath test to determine whether there is an infection of Helicobacter pylori. If the Helicobacter pylori infection is positive, a 14-day anti-Helicobacter pylori treatment should be administered. The treatment includes a proton pump inhibitor, two antibiotics, and a bismuth agent. After treatment, most of the Helicobacter pylori will convert from positive to negative.

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Written by Yang Chun Guang
Gastroenterology
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Can a gastroscopy detect Helicobacter pylori?

The examination with a gastroscope mainly focuses on checking for any damage to the mucous membranes of the stomach and esophagus. It can detect gastritis, gastric ulcers, or stomach cancer. For some patients who might have a tendency toward cancerous changes, a pathological examination can be conducted. However, testing for Helicobacter pylori with a gastroscope requires a separate lab test. Therefore, routine gastroscopic examinations generally do not include testing for Helicobacter pylori. If testing for Helicobacter pylori is needed, it is a separate examination item. Nowadays, since undergoing a gastroscopy can be quite uncomfortable and cause symptoms like nausea for some people, testing for Helicobacter pylori is accurately conducted using a breath test.

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Written by Si Li Li
Gastroenterology
1min 7sec home-news-image

How to treat Helicobacter pylori positive?

The infection rate of Helicobacter pylori in our country has already exceeded 50%, and Helicobacter pylori has been confirmed as the main cause of chronic gastritis, peptic ulcers, and even gastric cancer. If Helicobacter pylori tests positive and is accompanied by symptoms or diseases of the digestive system, eradication treatment for Helicobacter pylori is necessary. The medication involves a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with a treatment period of 14 days. After the 14-day treatment, the medication should be discontinued for a month before rechecking with a carbon-14 breath test to confirm whether Helicobacter pylori has turned negative. If it has turned negative, it indicates that the eradication treatment of Helicobacter pylori is successful. After infection with Helicobacter pylori, a diet easy to digest is recommended.

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Written by Jiang Guo Ming
Gastroenterology
1min 10sec home-news-image

Can a gastroscopy detect Helicobacter pylori?

First, it is important to clarify that a gastroscopy and a Helicobacter pylori test are two completely different methods. Generally speaking, a gastroscopy cannot detect whether there is a Helicobacter pylori infection. A gastroscopy specifically involves passing through the pharynx, esophagus, stomach, and finally reaching the descending part of the duodenum. It allows clear observation of whether there is inflammation, ulcers, or neoplastic diseases in the upper gastrointestinal tract, and it is the clearest and most direct method for examining the upper gastrointestinal tract. Helicobacter pylori testing, on the other hand, can generally be conducted in several ways. Firstly, blood can be drawn to test for Helicobacter pylori antibodies. Secondly, a breath test can be done, which is currently the most commonly used method, such as the carbon-13 or carbon-14 breath tests. Other methods include taking a biopsy during gastroscopy for a rapid urease test, and culturing bacteria from a biopsy. Therefore, gastroscopy cannot be used to test for Helicobacter pylori.

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Written by Wu Hai Wu
Gastroenterology
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Is Helicobacter pylori a serious illness?

Helicobacter pylori is not a major disease, so patients do not need to be overly anxious and worried. Once an infection of Helicobacter pylori is detected, patients can consider visiting the gastroenterology department of a formal hospital. The choice of medication should be based on the doctor's experience. Also, the use and dosage of the medication should be followed according to the doctor's instructions. For the treatment of Helicobacter pylori infections, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate the infection. During the treatment period, it is advisable to avoid eating spicy and irritating foods, and also to avoid alcohol, strong tea, coffee, etc. Avoid overeating and eat small, easily digestible meals more frequently. (Please follow the doctor’s prescription when using medication.)