Does pleural calcification easily turn into cancer?

Written by Wang Chun Mei

Pulmonology

Updated on February 11, 2025

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Pleurisy is a very common type of inflammatory lesion clinically. There are many factors that cause pleurisy, and it is generally seen in young and middle-aged males, mainly caused by Mycobacterium tuberculosis infection of the pleural cavity. If the pleurisy is tuberculous, it is usually treated with effective anti-tuberculosis medications systematically, which typically requires a course of 6 to 9 months. After complete recovery from pleurisy, many patients may show varying degrees of calcification spots in the pleural cavity. Generally, these calcification spots after recovery from pleurisy do not easily become cancerous.

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Written by Wang Chun Mei

Pulmonology

51sec

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What is the cause of hemoptysis in pleurisy?

Pleurisy is generally more commonly seen in young adults and children clinically, and is most commonly caused by an infection of the pleura by Mycobacterium tuberculosis. Usually, patients with this type of pleurisy do not experience symptoms of coughing up blood. The typical symptoms caused by pleurisy primarily include chest pain, coughing, chest tightness, shortness of breath, and in severe cases with a lot of pleural effusion, it can cause the patient to experience breathing difficulties and sometimes chills. Therefore, the clinical symptoms presented by different patients can vary. When a patient with pleurisy has a severe cough, it can lead to the rupture of the capillaries in the bronchial walls, which can cause the patient to have varying degrees of blood in the sputum, or even coughing up blood.

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Written by Li Hu Chen

Imaging Center

51sec

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Post-pleurisy chest X-ray presentation

Patients with pleurisy, after their recovery, often exhibit certain signs on chest X-rays, such as thickening and adhesion of the pleura, and blunting of the costophrenic angle. These conditions commonly arise because diseases like pleurisy might have a somewhat extended duration or are not detected timely, lacking prompt medical treatment. Hence, pleural thickening is prone to occur, visible on X-rays at the lung margins, where localized soft tissue density appears slightly thicker. Normally, the edge of the lung at the costophrenic angle would be quite sharp, but after pleural thickening, this angle becomes blunted or even rounded. In some cases, encapsulated effusions might be seen on a chest X-ray as a spindle-shaped high-density shadow near the chest wall, which appears as a notably bright shadow.

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Written by Zhang Zhi Gong

Cardiothoracic Surgery

49sec

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What are the symptoms of pleurisy and pneumothorax?

The pleural cavity in healthy individuals is a potential space and is under negative pressure. Its main purpose is to allow the lungs to fully adhere to the chest wall, and the lubricating fluid present serves to prevent too much friction between the lungs and chest wall during deep inhalation, which could cause pain. For various reasons, such as a ruptured lung bulla or trauma to the chest wall, a certain amount of air can enter the pleural cavity, leading to pain in patients. Due to the presence of pleurisy, friction occurs between the lungs and chest wall—particularly between the lower chest wall and the lungs—causing intense pain during deep inhalations. If a large volume of air is present, it can prevent the lungs from fully expanding, potentially leading to symptoms of breathing difficulties or an obstructed exhalation.

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Written by Xu Jun Hui

General Surgery

49sec

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The difference between pleurisy and peritonitis

Peritonitis generally refers to a severe disease caused by bacterial infection, chemical irritation, or injury, most of which are secondary peritonitis originating from infections and necrosis of abdominal organs, perforations, trauma, etc. The main symptoms include abdominal pain, tense abdominal muscles, tenderness, and board-like abdomen. Pleurisy generally refers to the inflammation of the pleura caused by pathogenic microorganisms, also known as pleuritis, which can be accompanied by pleural effusion. Pleurisy is commonly caused by tuberculosis. Generally, the symptoms of peritonitis are more severe than those of pleurisy. Both pleurisy and peritonitis require active, timely, and regular treatment.

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Written by Wang Chun Mei

Pulmonology

1min 3sec

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Is it normal to occasionally have chest pain with pleurisy?

Pleurisy is a very common type of disease, with many triggering factors. Most cases of pleurisy are caused by infection of the pleural cavity by Mycobacterium tuberculosis, leading to inflammatory lesions. Once pleurisy is diagnosed, patients should promptly receive anti-tuberculosis medication for effective treatment. It is commonly known that if pleurisy is not controlled promptly and effectively, it may lead to worsening symptoms such as cough, fever, shortness of breath, chest tightness, and chest pain, so these clinical symptoms are also very common in patients with pleurisy. Therefore, it is very common for patients with pleurisy to experience chest pain. Even after complete recovery from pleurisy, there may be varying degrees of chest pain, which is considered normal. This is because pleurisy in the acute phase may involve different degrees of adhesions, hence chest pain may occur later on as well.