Pleurisy is generally more commonly seen in young adults and children clinically, and is most commonly caused by an infection of the pleura by Mycobacterium tuberculosis. Usually, patients with this type of pleurisy do not experience symptoms of coughing up blood. The typical symptoms caused by pleurisy primarily include chest pain, coughing, chest tightness, shortness of breath, and in severe cases with a lot of pleural effusion, it can cause the patient to experience breathing difficulties and sometimes chills. Therefore, the clinical symptoms presented by different patients can vary. When a patient with pleurisy has a severe cough, it can lead to the rupture of the capillaries in the bronchial walls, which can cause the patient to have varying degrees of blood in the sputum, or even coughing up blood.