Ventricular septal defect is prone to complications with which diseases?

Written by Di Zhi Yong
Cardiology
Updated on April 17, 2025
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Ventricular septal defect is a type of congenital heart disease, and if a patient frequently experiences this condition, it can easily lead to heart failure. It particularly can cause arrhythmia. If a patient experiences palpitations, chest tightness, or states of ischemia and hypoxia, it needs to be addressed. Currently, the primary treatment for this disease is surgical. Patients should also be encouraged to regularly and frequently have echocardiographic check-ups. If the defect is relatively large, surgical treatment is recommended, and this surgery is also a type of minimally invasive procedure, which has very good outcomes.

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Written by Xie Zhi Hong
Cardiology
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What would happen if the ventricular septal defect occluder dislodges?

An occluder generally works like two umbrella surfaces clamped over the orifice of the interventricular septal defect, achieving the method whereby tissue blood flow enters from the left side of the septum to the right side. Once an occluder dislodges, it can lead to a dangerous situation, as the occluder has a membrane that can easily get caught on the tendons of the mitral valve, causing severe mitral regurgitation; it can also get stuck at the mitral valve orifice, obstructing the outflow of blood; it may also lead to aortic valve insufficiency; if it gets caught in the major arteries, it can cause arterial embolism, leading to sudden death in the patient. Therefore, the dislodgement of an occluder is a very dangerous phenomenon.

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Written by Fan Yan Fu
Cardiology
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Can someone with a ventricular septal defect travel by airplane?

Generally, individuals with ventricular septal defects (VSD) with no complications do not display symptoms and are able to travel by airplane. When such defects are at an early stage, where cardiac function has not been significantly impaired and there is left-to-right shunting without heart failure or pulmonary hypertension, flying is generally tolerated. After surgery for a ventricular septal defect, patients usually can fly. However, if the patient with a ventricular septal defect is older and in the advanced stages of the condition, exhibiting clear symptoms of heart failure such as difficulty breathing and chest tightness with significant exertional stress, such patients are unable to lie down and should not fly. Additionally, if there is right-to-left shunting or severe pulmonary hypertension has developed, it is unsafe for them to fly as they could potentially face emergencies during the flight.

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Written by Xie Zhi Hong
Cardiology
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Will being overweight affect the surgery for a ventricular septal defect?

Ventricular septal defect surgery is performed by puncturing the right femoral vein, guiding the catheter into the inferior vena cava, through the atria and ventricles, and reaching the defect via the right ventricle. The occluder can then be delivered through the catheter into the left ventricle, where the umbrella is opened, followed by opening it in the right ventricle; this describes the surgical process. Therefore, generally speaking, the surgical process is not affected in most patients who are obese. However, severe obesity can impact the accuracy of vascular localization during puncture by the surgeon. Secondly, if complications such as anesthesia issues or other emergencies arise during the surgery, severely obese patients may experience a reduced success rate in emergency surgical interventions, hence it is recommended that patients control their weight. Furthermore, severe obesity can exacerbate the cardiac load originally induced by the ventricular septal defect, thus affecting the surgical tolerance in patients whose cardiac function is already compromised by the defect. It is recommended that these patients control their weight.

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Written by Chen Tian Hua
Cardiology
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What are the complications of ventricular septal defect?

The complications of ventricular septal defect mainly include the following: 1. Causes infective endocarditis, with the highest incidence occurring between the ages of 15 and 29; 2. Leads to aortic valve insufficiency; 3. Causes conductive blockages; 4. Leads to heart failure, and can even lead to Eisenmenger syndrome. Therefore, patients with ventricular septal defects should actively complete examinations such as echocardiography. If there are indications for surgery, they should promptly visit a cardiac surgeon for active surgical treatment to correct the anatomical abnormalities of the ventricular septal defect and prevent the condition from worsening and leading to serious consequences.

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Written by Zhang Zhi Gong
Cardiothoracic Surgery
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Interventricular septal defect X-ray manifestation

X-ray Manifestations of Ventricular Septal Defect. These are mainly related to the size of the defect. If the ventricular septal defect is relatively small, for example less than three millimeters, the amount of blood shunted from the left ventricle to the right ventricular system is minimal. Consequently, right ventricular congestion is not pronounced, making pulmonary congestion also less obvious. At this point, the X-ray may show no significant changes. However, if the defect is larger, greater than three millimeters, for instance five millimeters, a large volume of high-pressure blood from the left ventricle will flow excessively through the defect into the right ventricular system. This leads to significant congestion in the right ventricle and, thus, in the entire pulmonary circulation. Additionally, the X-ray will show a prominent pulmonary artery segment and increased pulmonary blood flow. Moreover, over time, this condition may lead to compensatory enlargement of the left ventricular system. On the X-ray, enlargement of both the right and left ventricles can be observed. Furthermore, due to sustained high pressure, the distal pulmonary arteries may show signs of severe pulmonary vascular disease on the X-ray, resembling a broken book. This indicates that the pulmonary circulation has reached an end-stage condition.