After experiencing significant itching following a burn, the first consideration should be whether there is an infection or an allergic reaction. Observe the condition of the wound, thoroughly disinfect it with iodine to prevent infection, then apply mupirocin ointment or erythromycin ointment to the surface to treat the infection. Wrap with sterile gauze, and if necessary, apply ice packs to help relieve itching. Then take oral antibiotics, such as cefuroxime axetil capsules or levofloxacin capsules, for infection treatment, and take cetirizine or loratadine orally to manage allergies and alleviate symptoms. Additionally, maintain good hygiene, try to avoid exposure to air and raw water to prevent infections, and pay attention to diet. Avoid spicy and irritating foods, drink plenty of water, eat fresh vegetables and fruits to supplement vitamins, and consume high-protein, nutritious food to help improve the condition. (Medication should be used under the guidance of a physician.)