What is the full name of dementia?

Written by Zhang Hui
Neurology
Updated on November 30, 2024
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Senile dementia mainly refers to Alzheimer's disease, a condition with a relatively high incidence rate among the elderly population, and it is the most common neurodegenerative disease. The specific causes and mechanisms of this disease are not particularly clear. Under the influence of various factors, degeneration and death of the temporal lobe, hippocampus, and neurons occur, leading to a series of clinical manifestations. Initially, it mainly manifests as a decline in recent memory function, often forgetting recent events. As the disease progresses, there is a decline in calculating ability and judgment, significant spatial dysfunction, personality changes, and psychiatric symptoms.

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Written by Zhang Hui
Neurology
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Is senile dementia hereditary?

Dementia primarily refers to Alzheimer's disease, which mainly has two types: The first type is sporadic Alzheimer's disease, which does not have a clear familial history. It is caused by the degeneration and death of neurons due to various reasons, leading to certain clinical symptoms. This type of sporadic dementia does not have a genetic predisposition. The other type of dementia has a clear family history, where patients typically exhibit mutations in the APP gene, leading to increased secretion, which in turn causes the death of neurons and results in the symptoms of dementia. This familial type of dementia has a genetic predisposition. Dementia is a common condition in neurology and is the most common neurodegenerative disease. Currently, there are no effective treatments available. Family members must pay attention to caregiving, and patients can take cholinesterase inhibitors, which can improve symptoms to a certain extent.

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Written by Zhou Yan
Geriatrics
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Causes of Alzheimer's Disease

The causes of Alzheimer's disease are related to multiple factors. For instance, advanced age is the most significant risk factor for Alzheimer's disease, with the incidence increasing by 5% with each additional year. Secondly, it is related to gender, with women being more prone to Alzheimer's disease. Additionally, there is a certain relationship with genetics. The fourth factor is vascular factors, such as hypercholesterolemia, hyperhomocysteinemia, diabetes, and hypertension. The fifth factor is lifestyle, including smoking, excessive drinking, diet, sleep disorders, depression, and obesity, all of which are risk factors for Alzheimer's disease.

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Written by Zhang Hui
Neurology
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What can be done about senile dementia?

Once a patient is diagnosed with dementia, it is crucial to promptly visit a hospital for treatment. The doctor will conduct some auxiliary examinations based on the patient's medical history to rule out other diseases. If the diagnosis confirms dementia, firstly, family members must pay attention to care. The living abilities of patients with dementia decline significantly, and they may experience wandering, thus enhancing caregiving to prevent any accidents in the elderly; Secondly, it is essential to encourage the patient to engage in physical activities. Exercise can slow down the progression of aging and delay the further deterioration of dementia; Thirdly, it is vital to enhance communication for the patient, encouraging them to converse more with others, as interaction can slow down the progression of dementia; Fourthly, some specific medications should be administered for treatment. These drugs mainly include acetylcholinesterase inhibitors and NMDA receptor antagonists, which current research confirms can alleviate certain symptoms of dementia.

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Written by Zhang Hui
Neurology
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progression of Alzheimer's disease in the elderly

The progression of dementia in the elderly mainly includes the following aspects. The first is the pre-stage of mild cognitive impairment, during which patients show no clinical symptoms. Some may only report slight memory impairment, with a possible slight decline in learning ability and a mild decrease in the capability to learn new things. As the disease progresses to the second stage, the period of mild cognitive impairment occurs, where patients will experience impaired memory, but it is not particularly obvious, and daily life is not affected at all. Then, entering the third stage, some periods of dementia occur, during which patients' memory, executive abilities, computational skills, and judgment are significantly impaired. Patients might even get lost or possibly forget their own names. As the disease further progresses into the later stages of dementia, the elderly may exhibit some psychiatric symptoms. They become delirious, talk to themselves, and may see things that do not exist. Eventually, the elderly may end up bedridden, with complications such as pulmonary infections and bedsores.

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Written by Zhang Hui
Neurology
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Causes of Dementia

At present, the specific causes and mechanisms of Alzheimer's disease are not very clear, but they are mainly divided into two categories. The first category is hereditary, where some Alzheimer's disease cases have a clear family history and involve some genetic mutations. These genetic mutations lead to the deposition of abnormal proteins within neurons, causing irreversible neuronal death, which is the main reason for familial Alzheimer’s disease. The second category is sporadic Alzheimer’s disease, for which no clear pathogenesis has been identified. Research suggests that factors such as oxidative stress, trauma, cerebrovascular disease, cerebral ischemia, and other factors, including metabolic conditions leading to dementia, are related to the occurrence of sporadic Alzheimer's disease. Therefore, the causes of Alzheimer’s disease include two main categories: the first is caused by genetic mutations, and the second is caused by various adverse factors leading to neuronal death.