Causes of Alzheimer's Disease

Written by Zhou Yan

Geriatrics

Updated on April 10, 2025

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The causes of Alzheimer's disease are related to multiple factors. For instance, advanced age is the most significant risk factor for Alzheimer's disease, with the incidence increasing by 5% with each additional year. Secondly, it is related to gender, with women being more prone to Alzheimer's disease. Additionally, there is a certain relationship with genetics. The fourth factor is vascular factors, such as hypercholesterolemia, hyperhomocysteinemia, diabetes, and hypertension. The fifth factor is lifestyle, including smoking, excessive drinking, diet, sleep disorders, depression, and obesity, all of which are risk factors for Alzheimer's disease.

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Neurology

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probability of senile dementia

Dementia primarily refers to Alzheimer's disease, which has a relatively high incidence rate. In China, among the elderly population over 65 years old, approximately 3% to 7% are affected; this rate can rise to over 20% among those over 85 years old. Suffering from dementia places a heavy burden on the patient, their family, and society. Initially, patients with dementia will experience a decline in memory function. As the condition progresses, there will be a decline in various cognitive functions. For example, spatial dysfunction might occur, such as getting lost on the way home, personality changes, and the emergence of psychiatric symptoms and other clinical manifestations.

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Written by Zhang Hui

Neurology

46sec

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Early signs of dementia

Dementia in the elderly, mainly refers to Alzheimer's disease. Early signs of this condition may manifest as some forgetfulness. For example, a patient might forget to add salt while cooking, or forget to bring their keys when leaving the house. These clinical signs should be highly alarming and should not be dismissed as mere forgetfulness, ignoring further examinations and treatments. It is recommended that if the elderly show signs of diminished memory function, they should promptly visit a hospital. Comprehensive assessments and further tests, including brain MRI scans, should be conducted to check for significant atrophy in brain areas such as the temporal lobes and hippocampus. If dementia is diagnosed, prompt intervention and treatment should be pursued.

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Written by Zhang Hui

Neurology

59sec

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precursors of senile dementia

The diagnosis of senile dementia must first meet the diagnostic criteria for dementia, primarily characterized by impairment in multiple cognitive areas such as memory, language skills, executive function, and computational ability, and these impairments affect daily life; this is called senile dementia. Before dementia occurs, there are some precursory signs, mainly slight declines in memory. For example, patients might occasionally forget to bring keys when going out, or forget to turn off the stove while cooking. These mild memory impairments are some of the precursors to senile dementia. Additionally, there is a decline in learning ability, including the symptoms of learning new knowledge and mastering new skills; these declines are also precursors to senile dementia. Therefore, the precursors of senile dementia can primarily be summarized as a slight decline in memory function and some slight decline in learning ability.

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Written by Tang Bo

Neurology

37sec

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What is dementia called?

The commonly mentioned senile dementia, also known as Alzheimer's disease, is the most common type of dementia. Its incidence generally increases in people over the age of 65 and continues to increase with age. It is a degenerative disease, with risk factors including age and gender, usually higher in women than in men. It is also related to educational level, whether there has been trauma, genetics, thyroid function, exposure to toxic substances, as well as vascular factors. Diabetes and depression are also risk factors for senile dementia.

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Written by Zhang Hui

Neurology

1min 2sec

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symptoms of dementia in the elderly

The symptoms of dementia mainly include: First, impaired memory function, where the patient’s memory loss is very noticeable. Initially, they may not remember recent events, and as the disease progresses, they may not remember past events, such as forgetting how many children they have or their children’s names. Second, it mainly involves symptoms of impairment in other cognitive areas, such as visual spatial dysfunction, manifesting as not being able to find the bathroom at home, getting lost after going out, and not being able to find the way back home. Additionally, the patient's ability to understand, calculate, and judge will also be significantly impaired, and they cannot master previously learned knowledge and skills. Third, in the late stages, some psychiatric symptoms appear, including visual and auditory hallucinations, and agitated behaviors such as hitting and cursing. Additionally, the patient may also experience some physical weakness, muscle atrophy, and incontinence.