Why does pneumonia cause a decrease in white blood cells?

Written by Yang Li
Endocrinology
Updated on September 25, 2024
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When the severity of pneumonia is very severe, there can also be a decrease in white blood cells, which often suggests a higher possibility of severe pneumonia. Additionally, another scenario is viral pneumonia, where a decrease in white blood cells can also occur due to viral infections. Furthermore, there are special cases of infection, such as tuberculosis or infections caused by Mycoplasma or Chlamydia, where the use of anti-infection medications might also lead to a decrease in white blood cells. Another situation is when a patient inherently has a low white blood cell count, leading to weakened immunity and subsequently contracting pneumonia. In such cases, white blood cell counts might also not be high. Hence, severe bacterial pneumonia and decreases in white blood cells are relatively common in viral infections.

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Written by Yang Li
Endocrinology
57sec home-news-image

Why does pneumonia cause a decrease in white blood cells?

When the severity of pneumonia is very severe, there can also be a decrease in white blood cells, which often suggests a higher possibility of severe pneumonia. Additionally, another scenario is viral pneumonia, where a decrease in white blood cells can also occur due to viral infections. Furthermore, there are special cases of infection, such as tuberculosis or infections caused by Mycoplasma or Chlamydia, where the use of anti-infection medications might also lead to a decrease in white blood cells. Another situation is when a patient inherently has a low white blood cell count, leading to weakened immunity and subsequently contracting pneumonia. In such cases, white blood cell counts might also not be high. Hence, severe bacterial pneumonia and decreases in white blood cells are relatively common in viral infections.

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Written by Tang Zhuo
Endocrinology
1min 15sec home-news-image

What are the symptoms of leukopenia?

Leukopenia is a common hematological disorder that can occur at any age. It is defined as leukopenia when the total number of white blood cells in the peripheral blood consistently falls below four times ten to the ninth power per liter. The onset of this disease is usually gradual with mild symptoms such as fatigue, palpitations, dizziness, low fever, prone to pharyngitis or mucosal ulcerations, and also includes loss of appetite, limb fatigue, insomnia with frequent dreams, and a cold stomach and backache. It makes one more susceptible to viral and bacterial infections such as colds. If leukopenia is caused by an infection, common symptoms include high fever, chills, and body aches. If the total number of white blood cells is significantly reduced, with an absolute neutrophil count below 0.5 times ten to the ninth power per liter, it is referred to as neutropenia. In such cases, the patient may experience chills, high fever, sore throat, headache, joint pain, and in severe cases, even coma and death.

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Written by Liu Lei
Endocrinology
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What causes leukopenia?

Leukopenia mainly has the following three causes: 1) Drugs; 2) Infections; 3) Diseases that cause disturbances in white blood cell production. Drugs primarily include antibiotics such as sulfonamide antibiotics and penicillin; anti-tuberculosis drugs like rifampicin and isoniazid; anti-thyroid drugs such as methimazole and propylthiouracil; antipyretic analgesics like aminopyrine, indomethacin, and ibuprofen; and antihistamines such as diphenhydramine. Additionally, most chemotherapy drugs can cause a decrease in white blood cells. Viral infections can lead to a decrease in white blood cells or severe bacterial infections, such as sepsis and septicemia, along with some chronic infections. Diseases that cause disturbances in the production of white blood cells mainly refer to certain hematological diseases, such as aplastic anemia or malignant tumors that invade the bone marrow and affect hematopoiesis. Furthermore, there are some less common causes of leukopenia, such as familial inheritance and granulocyte distribution disorders.

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Written by Yang Li
Endocrinology
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Can leukopenia cause fever?

Leukopenia can lead to fever. White blood cells are the guardians of the human body, protecting it against external invasions such as infections. When white blood cells are decreased, the patient's resistance to infections can be significantly reduced, making them particularly susceptible to infections. This can lead to fever, as often seen in hematological patients with leukopenia who frequently experience fevers due to their chronic infection states. Therefore, when leukopenia is accompanied by fever, it is advisable to seek hospital treatment as soon as possible, as proactive infection management is crucial.

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Written by Zhang Jun Jun
Endocrinology
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Leukopenia and thrombocytopenia are what diseases

Diseases caused by decreased white blood cells and platelets are often related to our hematological system, since both white blood cells and platelets are produced by our hematopoietic factors. When there is a decrease in both white blood cells and platelets, we generally consider that there might be an issue with our hematopoietic system. The most common conditions could be diseases related to the hematological system, such as leukemia, or aplastic anemia. These conditions can cause a decrease in the mentioned indices. Another disease is cirrhosis, especially in patients in the compensatory stage, which can lead to hyperfunctioning of the spleen. The spleen is also an immune organ, as well as a part of our hematopoietic system, so when the spleen is hyperactive, it can also result in decreased white blood cells and platelets.