Gastric ulcer and duodenal ulcer

Written by Jiang Guo Ming
Gastroenterology
Updated on September 04, 2024
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Gastric ulcers and duodenal bulb ulcers both belong to upper gastrointestinal ulcers. Their symptoms slightly differ; gastric ulcers typically manifest as postprandial pain in the upper abdomen, whereas duodenal bulb ulcers present as hunger pains in the upper abdomen, sometimes accompanied by nocturnal pain. Both types generally exhibit symptoms such as acid reflux and heartburn. The predominant cause for these is infection by Helicobacter pylori, detectable through tests such as the carbon-13 or carbon-14 breath test. If an infection is present, antimicrobial treatment can typically lead to a complete recovery of the ulcers. If there is no Helicobacter pylori infection, the initial approach should still focus on symptomatic treatment. Additionally, adopting good dietary and living habits can facilitate regular gastroscopic follow-ups.

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Written by Jiang Guo Ming
Gastroenterology
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How to treat bleeding from gastric ulcers?

If it is a mild gastric ulcer bleeding, it may only manifest as black stool without any obvious specific discomfort symptoms and stable vital signs. This condition can be managed by controlling the diet and appropriately taking or intravenously using proton pump inhibitors such as omeprazole, lansoprazole, etc., which often can be curative. If the bleeding is considerable, presenting symptoms like vomiting coffee-colored or dark red liquid, fainting, profuse sweating, blood pressure drop, etc., this condition requires timely hospital treatment. Medication primarily includes proton pump inhibitors combined with hemostatic drugs, nutritional support, prevention of complications, etc. If the medical treatment is ineffective, endoscopic hemostasis might be needed, and further more, surgical intervention may be considered.

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Written by Jiang Guo Ming
Gastroenterology
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What medicine to take for gastric ulcer?

The stomach ulcers referred to here are generally benign gastric ulcers. The treatment plan should be determined based on whether there is a Helicobacter pylori infection. If there is no Helicobacter pylori infection, it is first important to develop good dietary and living habits, and then treat the symptoms, such as suppressing stomach acid, protecting the gastric mucosa, and increasing gastric motility. If there is a Helicobacter pylori infection, antibacterial treatment is needed. Typically, a triple or quadruple antibiotic therapy is used; a proton pump inhibitor plus two antibiotics constitute the triple therapy, and adding a bismuth agent constitutes the quadruple therapy. A course of treatment lasts for two weeks, which generally can eradicate the bacteria for a definitive cure. (Medications should be used under the guidance of a clinical doctor, according to specific conditions.)

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Written by Ren Zheng Xin
Gastroenterology
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How long does it take for a stomach ulcer to heal?

Gastric ulcers are a very common disease in gastroenterology. For minor ulcers, adjustments in diet, quitting smoking and drinking, consuming more green vegetables, getting more rest, and reducing mental stress can gradually lead to recovery. More severe ulcers require active medication use. To achieve ulcer healing, the course of acid-reducing medication usually lasts four to six weeks. Commonly used medications include those that inhibit gastric acid secretion, such as HR receptor antagonists and proton pump inhibitors, as well as some bismuth agents and weakly alkaline antacids to protect the stomach lining. Meanwhile, dietary management should be strengthened. Through effective medical treatment, the healing rate of gastric ulcers can reach over 95%. (Specific medication use should be conducted under the guidance of a doctor.)

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Written by Zhu Dan Hua
Gastroenterology
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What should I do if I have a stomach ulcer?

Gastric ulcers are generally treated with internal medicine medications in clinical settings, primarily through oral medications. Patients may select from antacid and stomach-protecting drugs for a course of 6-8 weeks, after which most ulcers can be healed. It is advised that patients eat clean, easily digestible foods, and avoid intake of spicy, stimulative, and pickled foods, as well as foods like raw fish and strong coffee. If the patient has a habit of drinking alcohol, it is advised to abstain from alcohol for these two months. It is also important to focus on resting and maintaining adequate sleep. Gastric ulcers are relatively common in clinical settings and generally improve with active treatment. Patients typically seek treatment for abdominal pain or complications, with the pain usually manifesting as upper abdominal pain. The most common complication is gastrointestinal bleeding, presenting as vomiting blood or bloody stools. Therefore, it is recommended that patients experiencing such discomfort should actively seek a comprehensive gastroscopy examination.

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Written by Li Xue Qing
Gastroenterology
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How to treat gastric ulcers?

The treatment of gastric ulcers mainly consists of general management and pharmacotherapy. General management involves patients avoiding spicy, stimulating, and cold foods, eating regular meals, and avoiding medications that may harm the stomach, such as non-steroidal anti-inflammatory drugs. Pharmacotherapy mainly includes gastroprotective therapy and treatment against Helicobacter pylori. Gastroprotective therapy includes neutralizing stomach acid with agents such as magnesium carbonate chewing tablets, acid-suppressing medications like proton pump inhibitors and H2 receptor antagonists, pantoprazole, cimetidine, etc. Medications to protect the gastric mucosa, such as sucralfate, bismuth preparations, etc., are also used. Treatment against Helicobacter pylori mainly includes triple and quadruple therapy. Triple therapy involves a proton pump inhibitor or a bismuth agent combined with two types of antibiotics, and quadruple therapy consists of a proton pump inhibitor, a bismuth agent, and two types of antibiotics. Antibiotics commonly used include amoxicillin, clarithromycin, furazolidone, levofloxacin, metronidazole, tetracycline, etc. Treatment generally lasts seven to ten days, with overall therapy for gastric ulcers spanning about a month. (Please undertake any medication under the guidance of a doctor.)