Parkinson's disease skin symptoms

Written by Zhou Yan
Geriatrics
Updated on April 16, 2025
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In Parkinson's disease, there are two main types of clinical manifestations. One is motor symptoms associated with damage to the dopaminergic system, and the other is non-motor symptoms related to damage of non-dopaminergic systems. The non-motor symptoms include olfactory dysfunction, sleep disorders, mood disorders, as well as cognitive and psychiatric behavioral disturbances. Additionally, there are dysfunctions of the autonomic nervous system, which manifest in the gastrointestinal tract mainly as constipation, and in the urinary system as urinary incontinence, urinary frequency, urinary retention, and sexual dysfunction. There also occurs orthostatic hypotension, along with changes in the skin. Some patients may experience abnormal increases or decreases in sweating and abnormal secretion of sebum in the facial area, which are specific skin symptoms of Parkinson's disease.

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Written by Zhang Hui
Neurology
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Where to treat Parkinson's disease

Parkinson's disease is a very common neurodegenerative disease in neurology. Therefore, if Parkinson's disease is suspected, treatment can be sought in the neurology department, which is available in most hospitals. Many neurologists have extensive experience in treating Parkinson's disease. The treatment primarily includes medication and surgery. Medication therapy mainly refers to the administration of anticholinergic drugs or dopamine receptor agonists, as well as preparations of Levodopa. These medications can help improve symptoms, such as reducing muscle rigidity and tremors. Surgical treatment mainly refers to deep brain stimulation, which is suitable for patients who have been clearly diagnosed with Parkinson's disease for over five years and whose primary symptom is tremor, without significant dementia.

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Can Parkinson's disease be cured?

Firstly, it must be noted that Parkinson's disease is a neurodegenerative disease which currently cannot be cured. Although Parkinson's disease cannot be cured, there are many methods available to slow the progression of the disease and improve the quality of life for patients. Patients must take medication regularly under the guidance of a doctor. The treatment methods for Parkinson's disease mainly include: First, patients should strengthen their functional training and engage in as much physical activity and exercise as possible, which can help in treating the disease. Second, regular medication is necessary, mainly referring to drugs used for treating Parkinson's disease. These include dopamine receptor agonists, anticholinergic drugs, and Levodopa preparations, all of which can have good effects, but these medications also have certain side effects and require regular follow-up visits at outpatient clinics. (Specific medications should be taken under the guidance of a physician.)

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Geriatrics
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How long does the course of Parkinson's disease usually last?

The course of Parkinson's disease generally lasts for how long? Parkinson's disease, also known as shaking palsy, is a common neurodegenerative disease, and the age at onset varies. For early-onset Parkinson's disease, it generally starts around age 40 to 50, while late-onset Parkinson's disease generally starts after age 50. As age gradually increases, the course of Parkinson's disease is generally about 20 to 40 years. Once diagnosed with Parkinson's disease, it is a lifelong condition. This disease is incurable, and can only be managed through medications, surgical treatments, physical rehabilitation, and psychological therapies to improve or control symptoms, but it cannot be cured. Therefore, once diagnosed with Parkinson's disease, the disease is lifelong.

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Causes of Parkinson's Disease

The cause of Parkinson's disease is mainly due to a part of the brain called the brainstem, which has some black moles and clusters containing a large number of neurons that can produce dopamine. The death of these neurons in the substantia nigra of the midbrain, caused by various factors, leads to Parkinson's disease. This results in noticeable slowness of movement in the limbs, muscle rigidity, as well as tremors, and unstable walking and other clinical manifestations. The causes of the death of dopaminergic neurons in the substantia nigra include genetic factors. Additionally, age is the biggest cause of the disease. Furthermore, dysfunctions in mitochondrial function, ischemia and hypoxia in the midbrain, certain traumas, and the use of drugs that deplete dopamine can all potentially cause Parkinson's disease.

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Is Parkinson's disease dangerous?

Parkinson's disease is a chronic condition and a progressive degenerative disorder of the nervous system. The main symptoms include slowed movements, increased muscle tone, resting tremors, and abnormal posture and gait. The onset of the disease is slow and subtly worsens over time. Although not highly dangerous in itself and not directly life-threatening, Parkinson’s disease currently lacks a cure, and the condition gradually worsens. Generally, within about 10 to 20 years, patients may experience significant balance impairments. The main risks involve instability while walking, which can lead to falls and potentially cause fractures and other complications. In later stages, patients often become bedridden, leading to possible complications such as pulmonary infections, urinary tract infections, bedsores, and malnutrition. Therefore, Parkinson's disease is relatively mild, manageable in the early stages, but requires careful attention in later stages to prevent complications and avoid unnecessary harm.