Early symptoms of Parkinson's disease
The clinical manifestations of Parkinson's disease are divided into two major categories. One category includes motor symptoms related to damage to the dopaminergic system. The other category includes non-motor symptoms related to damage to non-dopaminergic systems. The non-motor symptoms of Parkinson's disease can appear at various stages, especially before the onset of motor symptoms, such as loss of smell, rapid eye movement sleep behavior disorder, constipation, and depression, which are often early symptoms of the disease. However, because the onset of the disease in patients is relatively hidden, the initial symptoms are often tremors, but can also be bradykinesia or stiffness, with the majority of these cases being diagnosed based on these symptoms. Therefore, when a patient has loss of smell, constipation, depression, or sleep behavior disorder, the possibility of Parkinson's tremor paralysis should be considered.
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